The calcium ion (Ca2+) is the simplest and most versatile intracellular messenger known.
The discovery of Ca2+ sparks and a related family of elementary Ca2+ signaling events has …

Calcium signaling results from a complex interplay between activation and inactivation of
intracellular and extracellular calcium permeable channels. This complexity is obvious from …

Plants exhibit rapid, systemic signaling systems that allow them to coordinate physiological
and developmental responses throughout the plant body, even to highly localized and …

The complexity of cardiac electrophysiology, involving dynamic changes in numerous
components across multiple spatial (from ion channel to organ) and temporal (from …

The interactions between mathematics and physiology have a long and illustrious history, of
which the study of calcium signalling is but a small chapter. Nevertheless, for those involved …

Nuclear-associated oscillations in calcium act as a secondary messenger in the symbiotic
signaling pathway of legumes. These are decoded by a nuclear-localized calcium and …

Abstract The free [Ca 2+] in endoplasmic/sarcoplasmic reticulum Ca 2+ stores regulates
excitability of Ca 2+ release by stimulating the Ca 2+ release channels. Just how the stored …

This is a book on mathematical neuroscience, in which the unifying theme is wavelike
phenomena at multiple spatial and temporal scales. There are already several excellent …

In this manuscript we review the state of cardiac cell modelling in the context of international
initiatives such as the IUPS Physiome and Virtual Physiological Human Projects, which aim …

Atrial cardiomyocytes make an important contribution to the refilling of ventricles with blood,
which enhances the subsequent ejection of blood from the heart. The dependence of …