Treatment of spinal cord injury with mesenchymal stem cells

LL Liau, QH Looi, WC Chia, T Subramaniam, MH Ng… - Cell & bioscience, 2020 - Springer
Background Spinal cord injury (SCI) is the damage to the spinal cord that can lead to
temporary or permanent loss of function due to injury to the nerve. The SCI patients are often …

Heterogeneity of mesenchymal stem cells in cartilage regeneration: from characterization to application

K Zha, X Li, Z Yang, G Tian, Z Sun, X Sui… - NPJ Regenerative …, 2021 - nature.com
Articular cartilage is susceptible to damage but hard to self-repair due to its avascular
nature. Traditional treatment methods are not able to produce satisfactory effects …

Human umbilical cord mesenchymal stem cells: a new era for stem cell therapy

DC Ding, YH Chang, WC Shyu, SZ Lin - Cell transplantation, 2015 - journals.sagepub.com
The human umbilical cord is a promising source of mesenchymal stem cells (HUCMSCs).
Unlike bone marrow stem cells, HUCMSCs have a painless collection procedure and faster …

Exosomes Derived from Akt-Modified Human Umbilical Cord Mesenchymal Stem Cells Improve Cardiac Regeneration and Promote Angiogenesis via Activating …

J Ma, Y Zhao, L Sun, X Sun, X Zhao… - Stem cells …, 2017 - academic.oup.com
We have previously demonstrated the cardioprotective effects of exosomes derived from
mesenchymal stem cells (MSCs). It is well known that the activation of Akt is involved in stem …

Exosomes from human umbilical cord mesenchymal stem cells enhance fracture healing through HIF‐1α‐mediated promotion of angiogenesis in a rat model of …

Y Zhang, Z Hao, P Wang, Y Xia, J Wu, D Xia… - Cell …, 2019 - Wiley Online Library
Objectives Exosomes, as important players in intercellular communication due to their ability
to transfer certain molecules to target cells, are believed to take similar effects in promoting …

Exosomes isolated from human umbilical cord mesenchymal stem cells alleviate neuroinflammation and reduce amyloid-beta deposition by modulating microglial …

M Ding, Y Shen, P Wang, Z Xie, S Xu, ZY Zhu… - Neurochemical …, 2018 - Springer
Alzheimer's disease (AD) is the most common neurodegenerative disease characterized by
excessive accumulation of the amyloid-β peptide (Aβ) in the brain, which has been …

Mesenchymal stem cells for chronic wound healing: current status of preclinical and clinical studies

YZ Huang, M Gou, LC Da, WQ Zhang… - Tissue Engineering Part …, 2020 - liebertpub.com
Healing skin wounds with anatomic and functional integrity, especially under chronic
pathological conditions, remain an enormous challenge. Due to their outstanding …

[HTML][HTML] Umbilical cord-derived mesenchymal stem cells: their advantages and potential clinical utility

T Nagamura-Inoue, H He - World journal of stem cells, 2014 - ncbi.nlm.nih.gov
Human umbilical cord (UC) is a promising source of mesenchymal stem cells (MSCs). Apart
from their prominent advantages, such as a painless collection procedure and faster self …

Human umbilical cord-derived mesenchymal stem/stromal cells: a promising candidate for the development of advanced therapy medicinal products

M Mebarki, C Abadie, J Larghero, A Cras - Stem Cell Research & Therapy, 2021 - Springer
Umbilical cord-derived mesenchymal stem/stromal cells (UC-MSCs) emerge as a
perspective for therapeutic use in immune and inflammatory diseases. Indeed …

Immunosuppressive properties of mesenchymal stem cells: advances and applications

MP De Miguel, S Fuentes-Julian… - Current molecular …, 2012 - ingentaconnect.com
Mesenchymal stem cells (MSCs) have been isolated from a variety of tissues, such as bone
marrow, skeletal muscle, dental pulp, bone, umbilical cord and adipose tissue. MSCs are …