Modeling the effects of genetic-and diet-induced obesity on melanoma progression in zebrafish

E Montal, D Lumaquin, Y Ma… - Disease Models & …, 2023 - journals.biologists.com
Obesity is a rising concern and associated with an increase in numerous cancers, often in a
sex-specific manner. Preclinical models are needed to deconvolute the intersection between …

Single‐cell profiling of MC1R‐inhibited melanocytes

HM Berns, DE Watkins‐Chow, S Lu… - Pigment Cell & …, 2024 - Wiley Online Library
The human red hair color (RHC) trait is caused by increased pheomelanin (red‐yellow) and
reduced eumelanin (black‐brown) pigment in skin and hair due to diminished melanocortin …

[HTML][HTML] Loss of MC1R signaling implicates TBX3 in pheomelanogenesis and melanoma predisposition

HM Berns, DE Watkins-Chow, S Lu… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Abstract The human Red Hair Color (RHC) trait is caused by increased pheomelanin (red-
yellow) and reduced eumelanin (black-brown) pigment in skin and hair due to diminished …

Lipid droplets are a metabolic vulnerability in melanoma

D Lumaquin - 2022 - search.proquest.com
Melanoma exhibits numerous transcriptional cell states including neural crest-like cells as
well as pigmented melanocytic cells. How these different cell states relate to distinct …