[HTML][HTML] Mpox (formerly monkeypox): pathogenesis, prevention, and treatment

J Lu, H Xing, C Wang, M Tang, C Wu, F Ye… - … and Targeted Therapy, 2023 - nature.com
In 2022, a global outbreak of Mpox (formerly monkeypox) occurred in various countries
across Europe and America and rapidly spread to more than 100 countries and regions. The …

[HTML][HTML] Antivirals against monkeypox (Mpox) in humans: an updated narrative review

G Bruno, GB Buccoliero - Life, 2023 - mdpi.com
As of 29 August 2023, a total of 89,596 confirmed cases of Mpox (monkeypox) have been
documented across 114 countries worldwide, with 157 reported fatalities. The Mpox …

Tepotinib and tivantinib as potential inhibitors for the serine/threonine kinase of the mpox virus: Insights from structural bioinformatics analysis

JM Abduljalil, AA Elfiky… - Journal of Biomolecular …, 2024 - Taylor & Francis
The serine/threonine kinase (STK) plays a central role as the primary kinase in poxviruses,
directing phosphoryl transfer reactions. Such reactions are pivotal for the activation of certain …

Mpox treatment evolution: past milestones, present advances, and future directions

A Ganesan, T Arunagiri, S Mani, VR Kumaran… - Naunyn-Schmiedeberg's …, 2024 - Springer
An underestimated worldwide health concern, Monkeypox (Mpox) is becoming a bigger
menace to the world's population. After smallpox was eradicated in 1970, Mpox was found in …

[HTML][HTML] Repurposing amphotericin B and its liposomal formulation for the treatment of human Mpox

D Peruzzu, K Fecchi, G Venturi… - International Journal of …, 2023 - mdpi.com
Mpox (monkeypox) is a zoonotic viral disease caused by the mpox virus (MPXV). Recently in
2022, a multi-country Mpox outbreak has determined great concern as the disease rapidly …

[HTML][HTML] Therapeutic efficacy of tylvalosin combined with Poria cocos polysaccharides against porcine reproductive and respiratory syndrome

H Shi, W Luo, S Wang, J Dai, C Chen, S Li… - Frontiers in Veterinary …, 2023 - frontiersin.org
Porcine reproductive and respiratory syndrome (PRRS) is one of the most economically
important infectious diseases of pigs worldwide. Vaccination and various management …

[HTML][HTML] Mapping the Landscape of Health Research Priorities for Effective Pandemic Preparedness in Human Mpox Virus Disease

S Aggarwal, P Agarwal, K Nigam, N Vijay, P Yadav… - Pathogens, 2023 - mdpi.com
The global re-emergence of monkeypox (Mpox) in non-endemic regions in 2022 has
highlighted the critical importance of timely virus detection and robust public health …

Next-generation pediatric care: nanotechnology-based and AI-driven solutions for cardiovascular, respiratory, and gastrointestinal disorders

W de Alencar Morais Lima, JG de Souza… - World Journal of …, 2024 - Springer
Background Global pediatric healthcare reveals significant morbidity and mortality rates
linked to respiratory, cardiac, and gastrointestinal disorders in children and newborns …

Unleashing thymidylate kinase inhibitors: a computational quest against monkeypox virus

I Khater, A Nassar - Mathematics in Medical and Life Sciences, 2024 - Taylor & Francis
The rising incidence of monkeypox, a DNA virus-driven infectious disease, highlights the
urgent need for effective interventions. While disease severity varies among patients …

Molecular and phylogenetic characterization of the monkeypox outbreak in the South of Spain

CS Casimiro‐Soriguer, J Perez‐Florido… - Health Science …, 2024 - Wiley Online Library
Abstract Background and Aim Until the May 2022 Monkeypox (MPXV) outbreak, which
spread rapidly to many non‐endemic countries, the virus was considered a viral zoonosis …