One-quarter of photosynthesis-derived carbon on Earth rapidly cycles through a set of short-
lived seawater metabolites that are generated from the activities of marine phytoplankton …

All organisms produce specialized organic molecules, ranging from small volatile chemicals
to large gene-encoded peptides, that have evolved to provide them with diverse cellular and …

ColabFold offers accelerated prediction of protein structures and complexes by combining
the fast homology search of MMseqs2 with AlphaFold2 or RoseTTAFold. ColabFold's 40− 60 …

Abstract Late Pliocene and Early Pleistocene epochs 3.6 to 0.8 million years ago had
climates resembling those forecasted under future warming. Palaeoclimatic records show …

Metagenomes encode an enormous diversity of proteins, reflecting a multiplicity of functions
and activities,. Exploration of this vast sequence space has been limited to a comparative …

Protein language models have shown remarkable success in learning biological information
from protein sequences. However, most existing models are limited by either autoencoding …

DNA viruses have a major influence on the ecology and evolution of cellular organisms,,–,
but their overall diversity and evolutionary trajectories remain elusive. Here we carried out a …

Sequence comparison tools for metagenome-assembled genomes (MAGs) struggle with
high-volume or low-quality data. We present skani (https://github. com/bluenote-1577/skani) …

The impact of climate change on diversity, functioning and biogeography of marine plankton
remains a major unresolved issue. Here environmental niches are evidenced for plankton …

Biological nitrogen fixation contributes significantly to marine primary productivity. The
current view depicts few cyanobacterial diazotrophs as the main marine nitrogen fixers …