OBJECTIVE: Silymarin, extracted from the seeds of Silybum marianum L.(Milk thistle), is
traditionally used for treating various illnesses such as diabetes, cancer, inflammation …

Global surface waters are increasingly shown to be contaminated by anthropogenic
chemical pollutants which, in turn exert potential lethal-and sub-lethal toxicity risks to the …

Tramadol is a centrally acting analgesic generally used to treat moderate to severe pain.
This study was designed to evaluate the protective effect of Costus speciosus rhizome …

Background: Chemopreventive compounds may play an important role in cancer prevention.
However, many chemopreventive agents available currently are associated with toxicity …

Background: Opioids are addictive substances that have been shown to have neurotoxic
effects on the brain. These neurotoxic effects may be associated with retinal nerve fiber layer …

Endogenous opiod met-enkephalin throughout previous research manifested cytoprotective
and anti-inflammatory effects. Previous research suggests that met-enkephalin has …

Background: Genotoxicity screening of drugs is essential. It is mandatory for new drugs.
However, screening of drugs already in use is also necessary. Several cephalosporins are …

Introdução: Os opioides são compostos que interagem com os recetores opioides, e
possuem propriedades farmacológicas para o tratamento da dor moderada a severa. No …

Introduction: The met-enkephalin (1-5 Adrenorphin) and tridecactide (alpha-corticotropin 1-
13) combination is used in the multiple sclerosis (MS) immuno-modulatory treatment. A …

A crescente utilização de agrotóxicos com o intuito de aumentar a produção agrícola tornou-
se um dos principais problemas em relação ao meio ambiente. O solo é o primeiro …