Time for a full digital approach in nephropathology: a systematic review of current artificial intelligence applications and future directions

G Cazzaniga, M Rossi, A Eccher, I Girolami… - Journal of …, 2024 - Springer
Introduction Artificial intelligence (AI) integration in nephropathology has been growing
rapidly in recent years, facing several challenges including the wide range of histological …

Paving the path toward multi-omics approaches in the diagnostic challenges faced in thyroid pathology

I Piga, V L'Imperio, G Capitoli, V Denti… - Expert Review of …, 2023 - Taylor & Francis
Introduction Despite advancements in diagnostic methods, the classification of
indeterminate thyroid nodules still poses diagnostic challenges not only in pre-surgical …

[HTML][HTML] Congo red staining in digital pathology: the streamlined pipeline for amyloid detection through Congo red fluorescence digital analysis

G Cazzaniga, MM Bolognesi, MD Stefania… - Laboratory …, 2023 - Elsevier
Renal amyloidosis is a rare condition caused by the progressive accumulation of misfolded
proteins within glomeruli, vessels, and interstitium, causing functional decline and requiring …

The therapeutic potential of an allosteric non‐competitive CXCR1/2 antagonist for diabetic nephropathy

C Grasselli, S Bombelli, V D'Esposito… - Diabetes/Metabolism …, 2023 - Wiley Online Library
Aims Diabetic nephropathy is a major consequence of inflammation developing in type 1
diabetes, with interleukin‐8 (IL‐8)‐CXCR1/2 axis playing a key role in kidney disease …

Galileo—an Artificial Intelligence tool for evaluating pre-implantation kidney biopsies

A Eccher, V L'Imperio, L Pantanowitz, G Cazzaniga… - Journal of …, 2024 - Springer
Background Pre-transplant procurement biopsy interpretation is challenging, also because
of the low number of renal pathology experts. Artificial intelligence (AI) can assist by aiding …

[HTML][HTML] Natural Language Processing to extract SNOMED-CT codes from pathological reports

G Cazzaniga, A Eccher, E Munari, S Marletta… - Pathologica, 2023 - ncbi.nlm.nih.gov
Objective The use of standardized structured reports (SSR) and suitable terminologies like
SNOMED-CT can enhance data retrieval and analysis, fostering large-scale studies and …

Digital counting of tissue cells for molecular analysis: the QuANTUM pipeline

V L'Imperio, G Cazzaniga, M Mannino, D Seminati… - Virchows Archiv, 2024 - Springer
The estimation of tumor cellular fraction (TCF) is a crucial step in predictive molecular
pathology, representing an entry adequacy criterion also in the next-generation sequencing …

[HTML][HTML] Systemic vasculitis involving the kidney: the nephropathologist's point of view

V L'Imperio, S Ceola, B Cerbelli, A Barreca, F Pagni - Pathologica, 2024 - ncbi.nlm.nih.gov
Kidneys are often targets of systemic vasculitis (SVs), being affected in many different forms
and representing a possible sentinel of an underlying multi-organ condition. Renal biopsy …

Benchmarking digital displays (monitors) for histological diagnoses: the nephropathology use case

G Cazzaniga, F Mascadri, S Marletta… - Journal of Clinical …, 2024 - jcp.bmj.com
Aim The digital transformation of the pathology laboratory is being continuously sustained by
the introduction of innovative technologies promoting whole slide image (WSI)-based …

Improving the Annotation Process in Computational Pathology: A Pilot Study with Manual and Semi-automated Approaches on Consumer and Medical Grade Devices

G Cazzaniga, F Del Carro, A Eccher, JU Becker… - Journal of Imaging …, 2024 - Springer
The development of reliable artificial intelligence (AI) algorithms in pathology often depends
on ground truth provided by annotation of whole slide images (WSI), a time-consuming and …