Hospitals are breeding grounds for many life-threatening bacteria worldwide. Clinically
associated gram-positive bacteria such as Staphylococcus aureus/methicillin-resistant S …

Atomic force microscopy is an increasingly attractive tool to study how peptides disrupt
membranes. Often performed on reconstituted lipid bilayers, it provides access to time and …

Smp24, a cationic antimicrobial peptide identified from the venom gland of the Egyptian
scorpion Scorpio maurus palmatus, shows variable cytotoxicity on various tumor (KG1a …

Highlights•AFPs are promising sources of new antifungal agents.•The physiochemical and
biological properties of AFPs often need to be improved.•Rational design and combinatorial …

Non-small cell lung cancer (NSCLC) is the leading cause of death in lung cancer due to its
aggressiveness and rapid migration. The potent antitumor effect of Smp24, an antimicrobial …

Smp43, a cationic antimicrobial peptide identified from the venom gland of the Egyptian
scorpion Scorpio maurus palmatus, shows cytotoxicity toward hepatoma cell line HepG2 by …

The cytoplasmic membrane is one of the most frequent cell targets of antimicrobial peptides
(AMPs) and other biomolecules. Understanding the mechanism of action of AMPs at the …

Scorpion venoms have proven to be excellent sources of antimicrobial agents. However,
although many of them have been functionally characterized, they remain underutilized as …

Understanding the mechanism of action of antimicrobial peptides (AMP) is fundamental to
the development and design of peptide based antimicrobials. Utilizing fast-scan atomic force …

Within the last decade, several peptides have been identified according to their ability to
inhibit the growth of microbial pathogens. These antimicrobial peptides (AMPs) are a part of …