Global, regional and national burden of inflammatory bowel disease in 204 countries and territories from 1990 to 2019: a systematic analysis based on the Global …

R Wang, Z Li, S Liu, D Zhang - BMJ open, 2023 - bmjopen.bmj.com
Objectives We aimed to provide the most updated estimates on the global burden of
inflammatory bowel disease (IBD) to improve management strategies. Design We extracted …

How autophagy controls the intestinal epithelial barrier

EG Foerster, T Mukherjee, L Cabral-Fernandes… - Autophagy, 2022 - Taylor & Francis
Macroautophagy/autophagy is a cellular catabolic process that results in lysosome-
mediated recycling of organelles and protein aggregates, as well as the destruction of …

The epidemiology of inflammatory bowel disease: East meets west

WY Mak, M Zhao, SC Ng… - Journal of gastroenterology …, 2020 - Wiley Online Library
The incidence of inflammatory bowel diseases (IBD) in East has risen over the past decade
to become a global disease. The increasing number of studies on the incidence and course …

Immunotherapy for advanced hepatocellular carcinoma: a focus on special subgroups

M Pinter, B Scheiner, M Peck-Radosavljevic - Gut, 2021 - gut.bmj.com
Following the success of immune checkpoint blockers (ICBs) in different cancer types, a
large number of studies are currently investigating ICBs in patients with hepatocellular …

The global burden of IBD: from 2015 to 2025

GG Kaplan - Nature reviews Gastroenterology & hepatology, 2015 - nature.com
Over 1 million residents in the USA and 2.5 million in Europe are estimated to have IBD, with
substantial costs for health care. These estimates do not factor in the'real'price of IBD, which …

Urbanization and the gut microbiota in health and inflammatory bowel disease

T Zuo, MA Kamm, JF Colombel, SC Ng - … Reviews Gastroenterology & …, 2018 - nature.com
In the 21st century, urbanization represents a major demographic shift in developed and
developing countries. Rapid urbanization in the developing world has been associated with …

[HTML][HTML] Changing epidemiological trends of inflammatory bowel disease in Asia

WK Ng, SH Wong, SC Ng - Intestinal research, 2016 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) has become more common in Asia over the past few
decades. The rate of increase in prevalence of the disease varies greatly in Asia, with …

[HTML][HTML] Immune checkpoint inhibitor therapy in patients with preexisting inflammatory bowel disease

H Abu-Sbeih, DM Faleck, B Ricciuti… - Journal of Clinical …, 2020 - ncbi.nlm.nih.gov
PURPOSE The risk of immune checkpoint inhibitor therapy–related GI adverse events in
patients with cancer and inflammatory bowel disease (IBD) has not been well described. We …

Globalisation of inflammatory bowel disease: perspectives from the evolution of inflammatory bowel disease in the UK and China

GG Kaplan, SC Ng - The lancet Gastroenterology & hepatology, 2016 - thelancet.com
The UK and China provide unique historical perspectives on the evolution of the incidence
of inflammatory bowel disease, which might provide insight into its pathogenesis. Historical …

[HTML][HTML] Characteristics of fecal and mucosa-associated microbiota in Chinese patients with inflammatory bowel disease

L Chen, W Wang, R Zhou, SC Ng, J Li, M Huang… - Medicine, 2014 - journals.lww.com
The intestinal microbiota plays an important role in the pathogenesis of inflammatory bowel
disease (IBD), and geographical and genetic backgrounds impact the composition of the …