Biomolecular phase separation: from molecular driving forces to macroscopic properties

GL Dignon, RB Best, J Mittal - Annual review of physical …, 2020 - annualreviews.org
Biological phase separation is known to be important for cellular organization, which has
recently been extended to a new class of biomolecules that form liquid-like droplets …

Nanofibrils in nature and materials engineering

S Ling, DL Kaplan, MJ Buehler - Nature Reviews Materials, 2018 - nature.com
Nanofibrillar materials, such as cellulose, chitin and silk, are highly ordered architectures,
formed through the self-assembly of repetitive building blocks into higher-order structures …

Protein nanoparticles: promising platforms for drug delivery applications

A Jain, SK Singh, SK Arya, SC Kundu… - … Biomaterials Science & …, 2018 - ACS Publications
The development of drug delivery systems using nanoparticles as carriers for small and
large therapeutic molecules remains a rapidly growing area of research. The advantages of …

Protein polymer-based nanoparticles: fabrication and medical applications

K DeFrates, T Markiewicz, P Gallo, A Rack… - International journal of …, 2018 - mdpi.com
Nanoparticles are particles that range in size from about 1–1000 nanometers in diameter,
about one thousand times smaller than the average cell in a human body. Their small size …

Tropoelastin and elastin assembly

J Ozsvar, C Yang, SA Cain, C Baldock… - … in bioengineering and …, 2021 - frontiersin.org
Elastic fibers are an important component of the extracellular matrix, providing stretch,
resilience, and cell interactivity to a broad range of elastic tissues. Elastin makes up the …

Genetically Engineered Viral Vectors and Organic‐Based Non‐Viral Nanocarriers for Drug Delivery Applications

S Hajebi, S Yousefiasl, I Rahimmanesh… - Advanced …, 2022 - Wiley Online Library
Conventional drug delivery systems are challenged by concerns related to systemic toxicity,
repetitive doses, drug concentrations fluctuation, and adverse effects. Various drug delivery …

Recent trends in peptide and protein-based hydrogels

P Katyal, F Mahmoudinobar, JK Montclare - Current Opinion in Structural …, 2020 - Elsevier
Highlights•Hydrogels have revolutionized the field of biomaterials, with peptide and protein-
based systems emerging as versatile platforms.•Stimuli-responsive hydrogels respond to …

[HTML][HTML] A review of computational approaches used in the modelling, design, and manufacturing of biodegradable and biobased polymers

BG Laycock, CM Chan, PJ Halley - Progress in Polymer Science, 2024 - Elsevier
The design and manufacture of new biodegradable and bioderived polymeric materials has
traditionally taken place through experimentation and material characterisation. However …

Engineered Protein Hydrogels as Biomimetic Cellular Scaffolds

Y Liu, AE Gilchrist, SC Heilshorn - Advanced Materials, 2024 - Wiley Online Library
The biochemical and biophysical properties of the extracellular matrix (ECM) play a pivotal
role in regulating cellular behaviors such as proliferation, migration, and differentiation …

Stimuli-responsive composite biopolymer actuators with selective spatial deformation behavior

Y Wang, W Huang, Y Wang, X Mu… - Proceedings of the …, 2020 - National Acad Sciences
Bioinspired actuators with stimuli-responsive and deformable properties are being pursued
in fields such as artificial tissues, medical devices and diagnostics, and intelligent …