Branched-chain amino acids and insulin resistance, from protein supply to diet-induced obesity

JP De Bandt, X Coumoul, R Barouki - Nutrients, 2022 - mdpi.com
For more than a decade, there has been a wide debate about the branched-chain amino
acids (BCAA) leucine, valine, and isoleucine, with, on the one hand, the supporters of their …

Type 2 diabetes and succinate: unmasking an age-old molecule

S Fernández-Veledo, A Marsal-Beltran, J Vendrell - Diabetologia, 2024 - Springer
Beyond their conventional roles in intracellular energy production, some traditional
metabolites also function as extracellular messengers that activate cell-surface G-protein …

Exercise blood pressure and heart rate responses to graded exercise testing in intermediate versus morning chronotypes with obesity

MME Remchak, JK Dosik, G Pappas… - American Journal …, 2023 - journals.physiology.org
Exaggerated exercise blood pressure (BP) is linked to cardiovascular disease (CVD).
Although evening chronotypes have greater CVD risk than morning (Morn) types, it is …

Early chronotype with metabolic syndrome favours resting and exercise fat oxidation in relation to insulin‐stimulated non‐oxidative glucose disposal

SK Malin, MME Remchak, AJ Smith… - Experimental …, 2022 - Wiley Online Library
New Findings What is the central question of this study? Chronotype reflects differences in
circadian‐mediated metabolic and hormonal profiles. But, does resting and/or exercise fuel …

The relationship between sleep duration and metabolic syndrome severity scores in emerging adults

BA Chaudhry, MS Brian, JS Morrell - Nutrients, 2023 - mdpi.com
Background: Research suggests sleep duration can influence metabolic systems including
glucose homeostasis, blood pressure, hormone regulation, nervous system activity, and total …

Early chronotype favors appetite and reduced later day caloric intake among adults with obesity

SK Malin, USA Syeda, MME Remchak… - Chronobiology …, 2024 - Taylor & Francis
Late chronotype (LC) is related to obesity and altered food intake throughout the day. But
whether appetite perception and gut hormones differ among chronotypes is unclear. Thus …

Fasting Plasma Glucose and Glycated Hemoglobin Levels as Risk Factors for the Development of Hypertension: A Retrospective Cohort Study

B Luo, L Feng, Q Bi, R Shi, H Cao… - … Metabolic Syndrome and …, 2023 - Taylor & Francis
Introduction Hypertension (HTN) is a significant risk factor for cardiovascular disease.
Identifying new risk factors for hypertension is crucial. This study aims to determine the …

Aortic waveform responses to insulin in late versus early chronotype with metabolic syndrome

MME Remchak, EM Heiston, A Ballantyne… - Physiological …, 2022 - Wiley Online Library
Late chronotype (LC) correlates with reduced metabolic insulin sensitivity and
cardiovascular disease. It is unclear if insulin action on aortic waveforms and inflammation is …

Novel plasma metabolomic markers associated with diabetes progression in older puerto ricans

S Rivas-Tumanyan, LS Pacheco, DE Haslam, L Liang… - Metabolites, 2022 - mdpi.com
We assessed longitudinal associations between plasma metabolites, their network-derived
clusters, and type 2 diabetes (T2D) progression in Puerto Rican adults, a high-risk Hispanic …

Circadian rhythm sleep-wake disorders and the risk of dyslipidemia among railway workers in southwest China: A cross-sectional study

C Dong, H Liu, B Yang, J Pan, L Tang… - Chronobiology …, 2023 - Taylor & Francis
Railway workers are more likely to have an irregular work schedule, which had an effect on
their circadian rhythm of sleep, and may lead to circadian rhythm sleep-wake disorders …