Hepatic cholesterol transport and its role in non-alcoholic fatty liver disease and atherosclerosis

H Li, XH Yu, X Ou, XP Ouyang, CK Tang - Progress in lipid research, 2021 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a quickly emerging global health problem
representing the most common chronic liver disease in the world. Atherosclerotic …

[HTML][HTML] Recent insights on the role of cholesterol in non-alcoholic fatty liver disease

G Arguello, E Balboa, M Arrese, S Zanlungo - Biochimica et Biophysica …, 2015 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) encompasses a spectrum of hepatic
histopathological changes ranging from non-inflammatory intracellular fat deposition to non …

[HTML][HTML] Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice

BW Parks, E Nam, E Org, E Kostem, F Norheim, ST Hui… - Cell metabolism, 2013 - cell.com
Obesity is a highly heritable disease driven by complex interactions between genetic and
environmental factors. Human genome-wide association studies (GWAS) have identified a …

Cholesterol homeostasis: Researching a dialogue between the brain and peripheral tissues

M Gliozzi, V Musolino, F Bosco, M Scicchitano… - Pharmacological …, 2021 - Elsevier
Cholesterol homeostasis is a highly regulated process in human body because of its several
functions underlying the biology of cell membranes, the synthesis of all steroid hormones …

The Niemann-Pick type diseases–A synopsis of inborn errors in sphingolipid and cholesterol metabolism

FW Pfrieger - Progress in lipid research, 2023 - Elsevier
Disturbances of lipid homeostasis in cells provoke human diseases. The elucidation of the
underlying mechanisms and the development of efficient therapies represent formidable …

Predicting causal variants affecting expression by using whole-genome sequencing and RNA-seq from multiple human tissues

AA Brown, A Vinuela, O Delaneau, TD Spector… - Nature …, 2017 - nature.com
Genetic association mapping produces statistical links between phenotypes and genomic
regions, but identifying causal variants remains difficult. Whole-genome sequencing (WGS) …

The genetics of childhood obesity and interaction with dietary macronutrients

WS Garver, SB Newman, DM Gonzales-Pacheco… - Genes & nutrition, 2013 - Springer
The genes contributing to childhood obesity are categorized into three different types based
on distinct genetic and phenotypic characteristics. These types of childhood obesity are …

A multi-gene panel to identify lipedema-predisposing genetic variants by a next-generation sequencing strategy

S Michelini, KL Herbst, V Precone, E Manara… - Journal of Personalized …, 2022 - mdpi.com
Lipedema is a disabling disease characterized by symmetric enlargement of the lower
and/or upper limbs due to deposits of subcutaneous fat, that is easily misdiagnosed …

Genome-wide association study of body weight traits in chinese fine-wool sheep

Z Lu, Y Yue, C Yuan, J Liu, Z Chen, C Niu, X Sun… - Animals, 2020 - mdpi.com
Simple Summary Body weight traits are economically important in the sheep industry, and it
is critical to explore their underlying genetic architecture. Hence, four body weight traits …

Gene-nutrient interactions and susceptibility to human obesity

JJ Castillo, RA Orlando, WS Garver - Genes & nutrition, 2017 - Springer
A large number of genome-wide association studies, transferability studies, and candidate
gene studies performed in diverse populations around the world have identified gene …