Machine perfusion in kidney transplantation

A Kataria, S Magoon, B Makkar… - Current opinion in organ …, 2019 - journals.lww.com
Despite reduction in the rates of DGF by HMP, its effect on long-term renal and patient
outcomes is not clearly known. There is limited clinical literature in the use of normothermic …

Advances in hypothermic and normothermic perfusion in kidney transplantation

TB Smith, ML Nicholson, SA Hosgood - Transplantology, 2021 - mdpi.com
Hypothermic and normothermic machine perfusion in kidney transplantation are purported
to exert a beneficial effect on post-transplant outcomes compared to the traditionally used …

Brief normothermic machine perfusion rejuvenates discarded human kidneys

AM Hameed, DB Lu, E Patrick, BO Xu, M Hu… - Transplantation …, 2019 - journals.lww.com
Background. Normothermic machine perfusion (NMP) may allow resuscitation and improved
assessment of kidneys before transplantation. Using discarded human kidneys, we …

Pharmacologic targeting of renal ischemia-reperfusion injury using a normothermic machine perfusion platform

AM Hameed, DB Lu, H Burns, N Byrne, YV Chew… - Scientific Reports, 2020 - nature.com
Normothermic machine perfusion (NMP) is an emerging modality for kidney preservation
prior to transplantation. NMP may allow directed pharmacomodulation of renal ischemia …

[HTML][HTML] Improved normothermic machine perfusion after short oxygenated hypothermic machine perfusion of ischemically injured porcine kidneys

S Lignell, S Lohmann, KM Rozenberg… - Transplantation …, 2021 - journals.lww.com
Background. In an era where global kidney shortage has pushed the field of transplantation
towards using more marginal donors, modified kidney preservation techniques are currently …

[PDF][PDF] A novel, customized 3D-printed perfusion chamber for normothermic machine perfusion of the kidney

A Hameed, S Dervish, N Rogers, H Pleass… - Transpl. Int, 2019 - researchgate.net
Normothermic machine perfusion (NMP) prior to transplantation has gained significant
prominence in the recent past, and has been clinically utilized in the setting of liver, heart …

Initial experience: ex-vivo perfused pig kidney to study urinary oxalate excretion

JG Pavlinec, M Martin, W Donelan, E Kwenda… - Urolithiasis, 2022 - Springer
Existing animal models of renal oxalate excretion utilize either gut or peritoneal cavity for
oxalate absorption. Ex vivo renal perfusion is an established tool for graft preservation. We …

Pancreas and beta cell replacement: An overview

WJ Hawthorne - Pancreas and Beta Cell Replacement, 2022 - Elsevier
Since the concept of cell or tissue transplantation was first proposed over a century ago,
pancreas and islet cell transplantation have burgeoned into viable clinical therapies for …

[PDF][PDF] Brief normothermic machine perfusion rejuvenates discarded human kidneys–the potential for discard reduction and improved outcomes

A Hameed, D Lu, E Patrick, B Xu, M Hu… - Modifying Donor Organ …, 2016 - core.ac.uk
Introduction: Normothermic machine perfusion (NMP) is a promising new modality that
provides the potential for the resuscitation and improved assessment of kidneys prior to …

[引用][C] CD47-blockade to ameliorate kidney ischemia-reperfusion injury using normothermic machine perfusion–a small and large animal study

A Hameed, D Lu, H Burns, N Byrne, YV Chew, S Julovi… - Modifying Donor Organ …, 2016