Methyl-CpG-binding domain proteins: readers of the epigenome

Q Du, PL Luu, C Stirzaker, SJ Clark - Epigenomics, 2015 - Taylor & Francis
How DNA methylation is interpreted and influences genome regulation remains largely
unknown. Proteins of the methyl-CpG-binding domain (MBD) family are primary candidates …

[HTML][HTML] Folate and DNA methylation: a review of molecular mechanisms and the evidence for folate's role

KS Crider, TP Yang, RJ Berry, LB Bailey - Advances in nutrition, 2012 - Elsevier
ABSTRACT DNA methylation is an epigenetic modification critical to normal genome
regulation and development. The vitamin folate is a key source of the one carbon group …

Child health, developmental plasticity, and epigenetic programming

Z Hochberg, R Feil, M Constancia, M Fraga… - Endocrine …, 2011 - academic.oup.com
Plasticity in developmental programming has evolved in order to provide the best chances of
survival and reproductive success to the organism under changing environments …

Electrochemical, electrochemiluminescent and photoelectrochemical bioanalysis of epigenetic modifiers: A comprehensive review

Y Zhou, H Yin, WW Zhao, S Ai - Coordination Chemistry Reviews, 2020 - Elsevier
Epigenetic modifications mainly includes nucleic modifications and histone modifications,
which play crucial role in biological processes, such as gene and microRNA expression …

DNA methylation and methyl-CpG binding proteins: developmental requirements and function

O Bogdanović, GJC Veenstra - Chromosoma, 2009 - Springer
DNA methylation is a major epigenetic modification in the genomes of higher eukaryotes. In
vertebrates, DNA methylation occurs predominantly on the CpG dinucleotide, and …

Molecular coupling of DNA methylation and histone methylation

H Hashimoto, PM Vertino, X Cheng - Epigenomics, 2010 - Taylor & Francis
The combinatorial pattern of DNA and histone modifications constitutes an epigenetic 'code
'that shapes gene-expression patterns by enabling or restricting the transcriptional potential …

[HTML][HTML] Epigenetics of stress adaptations in the brain

AM Stankiewicz, AH Swiergiel, P Lisowski - Brain research bulletin, 2013 - Elsevier
Recent findings in epigenetics shed new light on the regulation of gene expression in the
central nervous system (CNS) during stress. The most frequently studied epigenetic …

Cancer DNA methylation: molecular mechanisms and clinical implications

MT McCabe, JC Brandes, PM Vertino - Clinical Cancer Research, 2009 - AACR
DNA methylation plays a crucial role in the regulation of gene expression and chromatin
organization within normal eukaryotic cells. In cancer, however, global patterns of DNA …

Epigenetic responses to environmental change and their evolutionary implications

BM Turner - … Transactions of the Royal Society B …, 2009 - royalsocietypublishing.org
Chromatin is a complex of DNA, RNA, histones and non-histone proteins and provides the
platform on which the transcriptional machinery operates in eukaryotes. The structure and …

Epigenetic modifications of gene expression by lifestyle and environment

QA Abdul, BP Yu, HY Chung, HA Jung… - Archives of pharmacal …, 2017 - Springer
Epigenetics oftenly described as the heritable changes in gene expression independent of
changes in DNA sequence. Various environmental factors such as nutrition-dietary …