ABSTRACT DNA methylation is an epigenetic modification critical to normal genome regulation and development. The vitamin folate is a key source of the one carbon group …
Plasticity in developmental programming has evolved in order to provide the best chances of survival and reproductive success to the organism under changing environments …
Y Zhou, H Yin, WW Zhao, S Ai - Coordination Chemistry Reviews, 2020 - Elsevier
Epigenetic modifications mainly includes nucleic modifications and histone modifications, which play crucial role in biological processes, such as gene and microRNA expression …
DNA methylation is a major epigenetic modification in the genomes of higher eukaryotes. In vertebrates, DNA methylation occurs predominantly on the CpG dinucleotide, and …
H Hashimoto, PM Vertino, X Cheng - Epigenomics, 2010 - Taylor & Francis
The combinatorial pattern of DNA and histone modifications constitutes an epigenetic 'code 'that shapes gene-expression patterns by enabling or restricting the transcriptional potential …
AM Stankiewicz, AH Swiergiel, P Lisowski - Brain research bulletin, 2013 - Elsevier
Recent findings in epigenetics shed new light on the regulation of gene expression in the central nervous system (CNS) during stress. The most frequently studied epigenetic …
DNA methylation plays a crucial role in the regulation of gene expression and chromatin organization within normal eukaryotic cells. In cancer, however, global patterns of DNA …
BM Turner - … Transactions of the Royal Society B …, 2009 - royalsocietypublishing.org
Chromatin is a complex of DNA, RNA, histones and non-histone proteins and provides the platform on which the transcriptional machinery operates in eukaryotes. The structure and …
QA Abdul, BP Yu, HY Chung, HA Jung… - Archives of pharmacal …, 2017 - Springer
Epigenetics oftenly described as the heritable changes in gene expression independent of changes in DNA sequence. Various environmental factors such as nutrition-dietary …