The corpus callosum is the largest fibre tract in the brain, connecting the two cerebral
hemispheres, and thereby facilitating the integration of motor and sensory information from …

Recent advances in our understanding of the underlying genetic architecture of psychiatric
disorders has blown away the diagnostic boundaries that are defined by currently used …

Adult neurogenesis occurs throughout life in discrete regions of the adult mammalian brain.
Little is known about the mechanism governing the sequential developmental process that …

The DISC locus is located at the breakpoint of a balanced t (1; 11) chromosomal
translocation in a large and unique Scottish family. This translocation segregates in a highly …

Mutations of DISC1 (disrupted-in-schizophrenia 1) have been associated with major
psychiatric disorders. Despite the hundreds of DISC1-binding proteins reported, almost …

Summary Disrupted-in-schizophrenia 1 (DISC1), a susceptibility gene for major mental
illnesses, regulates multiple aspects of embryonic and adult neurogenesis. Here, we show …

A strong candidate gene for schizophrenia and major mental disorders, disrupted-in-
schizophrenia 1 (DISC1) was first described in a large Scottish family in which a balanced …

In the decade since Disrupted in Schizophrenia 1 (DISC1) was first identified it has become
one of the most convincing risk genes for major mental illness. As a multi-functional scaffold …

The biology of schizophrenia is complex with multiple hypotheses (dopamine, glutamate,
neurodevelopmental) well supported to underlie the disease. Pathways centered on the risk …

Exosomes (EXs) are emerging as novel players in the beneficial effects induced by exercise
on vascular diseases. We have recently revealed that moderate exercise enhances the …