Aminolevulinic acid (ALA) is an endogenous metabolite normally formed in the mitochondria
from succinyl-CoA and glycine. Conjugation of eight ALA molecules yields protoporphyrin IX …

Photodynamic therapy (PDT) is an attractive therapy for non‐melanoma skin cancers
including actinic keratoses (AKs) because it allows treatment of large areas; it has a high …

In photodynamic therapy, light is absorbed by a therapy agent (photosensitizer) to generate
reactive oxygen, which then locally kills diseased cells. Here, we report a new form of …

Photodynamic therapy (PDT) induced by protoporphyrin IX (PpIX) has been widely used in
dermatological practices such as treatment of skin cancers. Clearance rate depends on …

Targeting the tumor microenvironment (TME) provides opportunities to modulate tumor
physiology, enhance the delivery of therapeutic agents, impact immune response and …

Pain during photodynamic therapy (PDT) is the main limiting adverse effect in its use in
dermatology. Given its multifactorial nature, we reviewed both intrinsic and extrinsic factors …

Background Photodynamic therapy (PDT) is an attractive therapy for nonmelanoma skin
cancers and actinic keratoses (AKs). Daylight‐mediated methyl aminolaevulinate PDT …

The response rates of photodynamic therapy (PDT) vary widely. Limited uptake of topically
applied 5-aminolaevulinic acid (ALA), or its methyl ester (MAL), and suboptimal production …

Background The incidence of actinic keratoses (AK) and non‐melanoma skin cancer
(NMSC) in organ transplant recipients (OTRs) is significantly higher than in …

In this study, we describe a photocatalytic system based on spherical fluorescent carbon-
core nanoparticles (nanodots) that can be activated with ultraviolet radiation. The carbon …