Alzheimer's disease (AD) is a progressive neurological disease characterized by the loss of
cognitive function, confusion, and memory deficit. Accumulation of abnormal proteins …

Amyloid-β (Aβ) 1-40 and 1-42 peptides are key mediators of synaptic and cognitive
dysfunction in Alzheimer's disease (AD). Whereas in AD, Aβ is found to act as a pro …

Alzheimer's disease is a neurodegenerative disease characterized by deposition of
extracellular amyloid‐β, intracellular neurofibrillary tangles, and loss of cortical neurons …

Background: Oxidative stress has been implicated in Alzheimer's disease (AD) as a common
pathway underlying neuronal damage causing huge impacts on cognitive functions in the …

Alzheimer's Disease (AD) is a neurodegenerative disease featured by cognitive impairment.
This bioinformatic analysis was used to identify hub genes related to cognitive dysfunction in …

Our recent work on genetic epilepsy (GE) has identified common mechanisms between GE
and neurodegenerative diseases including Alzheimer's disease (AD). Although both …

We used ChR2-assisted circuit mapping (CRACM) to examine neuronal/compartmental
excitatory and inhibitory synaptic balance (EI balance) in pyramidal cells (PCs) located in …

Accumulating clinical data indicates that insulin resistance and diabetes mellitus (DM) are
major risk factors for Alzheimer's disease (AD); however, the exact mechanisms on how …

Triptolide is an epoxidized diterpene lactone isolated from Tripterygium wilfordii. Studies
have shown that triptolide exerts organ‐protective effects. However, it remains unknown …

Objectives Neuropsychiatric symptoms (NPSs) in those with major neurocognitive disorder
(MNCD) include the responsive behaviors of agitation and aggression. Electroconvulsive …