Estradiol as the trigger of sirtuin-1-dependent cell signaling with a potential utility in anti-aging therapies

K Karolczak, C Watala - International Journal of Molecular Sciences, 2023 - mdpi.com
Aging entails the inevitable loss of the structural and functional integrity of cells and tissues
during the lifetime. It is a highly hormone-dependent process; although, the exact …

The emerging role of dipeptidyl peptidase 3 in pathophysiology

G Malovan, B Hierzberger, S Suraci… - The FEBS …, 2023 - Wiley Online Library
Dipeptidyl peptidase 3 (DPP3), a zinc‐dependent aminopeptidase, is a highly conserved
enzyme among higher animals. The enzyme cleaves dipeptides from the N‐terminus of tetra …

Dipeptidyl peptidase 3 modulates the renin–angiotensin system in mice

S Jha, U Taschler, O Domenig, M Poglitsch… - Journal of Biological …, 2020 - ASBMB
Dipeptidyl peptidase 3 (DPP3) is a zinc-dependent hydrolase involved in degrading
oligopeptides with 4–12 amino acid residues. It has been associated with several …

Involvement of DPP3 in modulating oncological features and oxidative stress response in esophageal squamous cell carcinoma

M Arora, S Kumari, L Kadian, G Anupa… - Bioscience …, 2023 - portlandpress.com
Resistance to therapy in esophageal squamous cell carcinoma (ESCC) is a critical clinical
problem and identification of novel therapeutic targets is highly warranted. Dipeptidyl …

Trefoil factor 3 deficiency affects liver lipid metabolism

M Bujak, IT Bujak, S Sobočanec, M Mihalj… - Cellular physiology and …, 2018 - karger.com
Abstract Background/Aims: Tff3 protein plays a well recognized role in the protection of
gastrointestinal mucosa. The role of Tff3 in the metabolism is a new aspect of its function …

17beta-estradiol alleviates contusion-induced skeletal muscle injury by decreasing oxidative stress via SIRT1/PGC-1α/Nrf2 pathway

X Tian, Z Gao, D Yin, Y Hu, B Fang, C Li, S Lou, Z Rao… - Steroids, 2023 - Elsevier
Purpose This study aimed to investigate the role of 17β-estradiol (E 2) in the repair of
contusion-induced myoinjury in mice and to identify the underlying molecular mechanisms …

Identification of SH2 Domain-Containing Protein 3C as a Novel, Putative Interactor of Dipeptidyl Peptidase 3

M Matovina, A Tomašić Paić, S Tomić, H Brkić… - International journal of …, 2023 - mdpi.com
Dipeptidyl peptidase 3 (DPP3) is a zinc-dependent exopeptidase with broad specificity for
four to eight amino acid residue substrates. It has a role in the regulation of oxidative stress …

The oxygen concentration in cultures modulates protein expression and enzymatic antioxidant responses in Metarhizium lepidiotae conidia

N García-Ortiz, FJ Figueroa-Martínez… - Fungal biology, 2018 - Elsevier
Conidia from Metarhizium spp. are used for integrated pest control; however, environmental
factors diminish the effectivity of these programs. Several approaches tried to improve …

Dynamic properties of dipeptidyl peptidase III from Bacteroides thetaiotaomicron and the structural basis for its substrate specificity–a computational study

M Tomin, S Tomić - Molecular biosystems, 2017 - pubs.rsc.org
Dipeptidyl peptidase III (DPP III) from the human gut symbiont Bacteroides thetaiotaomicron
(Bt) is the first identified prokaryotic DPP III orthologue. It has low sequence similarity to the …

Istraživanje biokemijskih osobina mutiranih inačica dipeptidil-peptidaze III, R510W i V514M te njihovog utjecaja na regulaciju signalnog puta Nrf2/Keap1; Enzimi …

DC Kindl - 2023 - repozitorij.pmf.unizg.hr
Sažetak Diplomski rad sastoji se od eksperimentalnog i metodičkog dijela. U
eksperimentalnom dijelu ispitane su biokemijske osobine mutiranih inačica R510W i V514M …