The multiscale physics of cilia and flagella

W Gilpin, MS Bull, M Prakash - Nature Reviews Physics, 2020 - nature.com
Cilia and flagella are fundamental units of motion in cellular biology. These beating, hair-like
organelles share a common basic structure but maintain widely varying functions in systems …

Fluid-structure interaction of bio-inspired flexible slender structures: A review of selected topics

C Wang, H Tang, X Zhang - Bioinspiration & biomimetics, 2022 - iopscience.iop.org
Flexible slender structures are ubiquitous in biological systems and engineering
applications. Fluid-structure interaction (FSI) plays a key role in the dynamics of such …

Metachronal patterns in artificial cilia for low Reynolds number fluid propulsion

E Milana, R Zhang, MR Vetrano, S Peerlinck… - Science …, 2020 - science.org
Cilia are hair-like organelles, present in arrays that collectively beat to generate flow. Given
their small size and consequent low Reynolds numbers, asymmetric motions are necessary …

Motile cilia create fluid-mechanical microhabitats for the active recruitment of the host microbiome

JC Nawroth, H Guo, E Koch… - Proceedings of the …, 2017 - National Acad Sciences
We show that mucociliary membranes of animal epithelia can create fluid-mechanical
microenvironments for the active recruitment of the specific microbiome of the host. In …

Multi-scale spatial heterogeneity enhances particle clearance in airway ciliary arrays

GR Ramirez-San Juan, AJTM Mathijssen, M He, L Jan… - Nature physics, 2020 - nature.com
Mucus clearance constitutes the primary defence of the respiratory system against viruses,
bacteria and environmental insults. This transport across the entire airway emerges from the …

Metachronal motion across scales: current challenges and future directions

ML Byron, DW Murphy, K Katija… - Integrative and …, 2021 - academic.oup.com
Metachronal motion is used across a wide range of organisms for a diverse set of functions.
However, despite its ubiquity, analysis of this behavior has been difficult to generalize …

[HTML][HTML] Mechanisms and functions of multiciliary coordination

KY Wan, RN Poon - Current Opinion in Cell Biology, 2024 - Elsevier
Ciliated organisms are present in virtually every branch of the eukaryotic tree of life. In
diverse systems, cilia operate in a coordinated manner to drive fluid flows, or even propel …

Transport and mixing by metachronal waves in nonreciprocal soft robotic pneumatic artificial cilia at low Reynolds numbers

R Zhang, J den Toonder, PR Onck - Physics of Fluids, 2021 - pubs.aip.org
Cilia are widely employed by living systems to manipulate fluid flow in various functions,
such as feeding, pumping, and locomotion. Mimicking the intricate ciliary asymmetry in …

Instability-driven oscillations of elastic microfilaments

F Ling, H Guo, E Kanso - Journal of The Royal Society …, 2018 - royalsocietypublishing.org
Cilia and flagella are highly conserved slender organelles that exhibit a variety of rhythmic
beating patterns from non-planar cone-like motions to planar wave-like deformations …

Swimming mediated by ciliary beating: comparison with a squirmer model

H Ito, T Omori, T Ishikawa - Journal of Fluid Mechanics, 2019 - cambridge.org
The squirmer model of Lighthill and Blake has been widely used to analyse swimming
ciliates. However, real ciliates are covered by hair-like organelles, called cilia; the …