A comprehensive review on the role of the gut microbiome in human neurological disorders

SG Sorboni, HS Moghaddam… - Clinical microbiology …, 2022 - Am Soc Microbiol
The human body is full of an extensive number of commensal microbes, consisting of
bacteria, viruses, and fungi, collectively termed the human microbiome. The initial …

The microbiota-gut-brain axis: from motility to mood

KG Margolis, JF Cryan, EA Mayer - Gastroenterology, 2021 - Elsevier
The gut-brain axis plays an important role in maintaining homeostasis. Many intrinsic and
extrinsic factors influence signaling along this axis, modulating the function of both the …

The gut microbiota–brain axis in behaviour and brain disorders

LH Morais, HL Schreiber IV… - Nature Reviews …, 2021 - nature.com
In a striking display of trans-kingdom symbiosis, gut bacteria cooperate with their animal
hosts to regulate the development and function of the immune, metabolic and nervous …

The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

AHR in the intestinal microenvironment: safeguarding barrier function

B Stockinger, K Shah, E Wincent - Nature reviews Gastroenterology & …, 2021 - nature.com
Mammalian aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor that
belongs to the basic helix–loop–helix (bHLH)–PAS family of transcription factors, which are …

The human gut microbiome–a potential controller of wellness and disease

ZY Kho, SK Lal - Frontiers in microbiology, 2018 - frontiersin.org
Interest toward the human microbiome, particularly gut microbiome has flourished in recent
decades owing to the rapidly advancing sequence-based screening and humanized …

Enteric glial biology, intercellular signalling and roles in gastrointestinal disease

L Seguella, BD Gulbransen - Nature reviews Gastroenterology & …, 2021 - nature.com
One of the most transformative developments in neurogastroenterology is the realization that
many functions normally attributed to enteric neurons involve interactions with enteric glial …

The role of gut dysbiosis in Parkinson's disease: mechanistic insights and therapeutic options

Q Wang, Y Luo, K Ray Chaudhuri, R Reynolds, EK Tan… - Brain, 2021 - academic.oup.com
Parkinson's disease is a common neurodegenerative disorder in which gastrointestinal
symptoms may appear prior to motor symptoms. The gut microbiota of patients with …

Gut–brain axis: role of gut microbiota on neurological disorders and how probiotics/prebiotics beneficially modulate microbial and immune pathways to improve brain …

K Suganya, BS Koo - International journal of molecular sciences, 2020 - mdpi.com
The gut microbiome acts as an integral part of the gastrointestinal tract (GIT) that has the
largest and vulnerable surface with desirable features to observe foods, nutrients, and …

Intestinal microbiota shapes gut physiology and regulates enteric neurons and glia

FA Vicentini, CM Keenan, LE Wallace, C Woods… - Microbiome, 2021 - Springer
Background The intestinal microbiota plays an important role in regulating gastrointestinal
(GI) physiology in part through interactions with the enteric nervous system (ENS) …