Factors affecting attitudes toward migrants—An evolutionary approach

A Schahbasi, S Huber, M Fieder - American Journal of Human …, 2021 - Wiley Online Library
Objective To understand migration from an evolutionary perspective, this phenomenon has
so far been mainly investigated in animal species. We therefore aim to investigate the …

Next Generation Sequencing of Genotype Variants and Genetic Association between Heat Shock Proteins HSPA1B Single Nucleotide Polymorphism at the g …

FO Alele, JR Otto, BS Malau-Aduli, AEO Malau-Aduli - Biomolecules, 2022 - mdpi.com
Heat tolerance and exertional heat stroke (EHS) are rare health conditions that have been
described and characterised but have never been genetically solved. Knowledge of the role …

Genomic heterozygosity is associated with a lower risk of osteoarthritis

R Gill, M Liu, G Sun, A Furey, T Spector, P Rahman… - BMC genomics, 2024 - Springer
Background Genomic heterozygosity has been shown to confer a health advantage in
humans and play a protective role in complex diseases. Given osteoarthritis (OA) is a highly …

Role of MTHFR, IRF6, PAX7 and TP63 SNPs in susceptibility to non‐syndromic orofacial cleft, a candidate gene study in a Portuguese population

J Mendes, AR Guimarães, JM Ribeiro… - Orthodontics & …, 2024 - Wiley Online Library
Background Non‐syndromic orofacial cleft (NSOC) is a complex phenotype, involving
multiple genetic and environmental factors. Association studies exploring the genetic …

[HTML][HTML] Analyses of allele age and fitness impact reveal human beneficial alleles to be older than neutral controls

AM Pivirotto, A Platt, R Patel, S Kumar, J Hey - bioRxiv, 2023 - ncbi.nlm.nih.gov
A classic population genetic prediction is that alleles experiencing directional selection
should swiftly traverse allele frequency space, leaving detectable reductions in genetic …

Haematological Indicators of Response to Erythropoietin Therapy in Chronic Renal Failure Patients on Haemodialysis: Impact of Angiotensin-Converting Enzyme …

A Hamdan Almaeen… - Pharmacogenomics and …, 2021 - Taylor & Francis
Purpose This is the first cross-sectional study studying the changes in haematological
indicators of the response to recombinant human erythropoietin (rHuEPO) therapy in chronic …

Glutathione S‐Transferase Omega‐2 and Transforming Growth Factor‐β1 Polymorphisms in Iranian Glaucoma Patients

S Bamdad, F Sanie-Jahromi… - Journal of …, 2021 - Wiley Online Library
Background. To investigate the association of glutathione s‐transferase omega 2
(GSTO2)(142N> D) and transforming growth factor‐β1 (TGF‐β1)(869T> C) gene …

Association between three variants in the PRKAA2 gene, rs2796498, rs9803799, and rs2746342, with 10-year ASCVD risk on newly diagnosed T2DM in Yogyakarta …

DM Virginia, MSH Wahyuningsih… - … Macedonian Journal of …, 2021 - oamjms.eu
BACKGROUND: AMPK has pivotal roles in glucose and lipid metabolism, including
AMPKa2, which PRKAA2 encodes. Metformin as an anti-hyperglycemia agent acts through …

Analyses of allele age and fitness impact reveal human beneficial alleles to be older than neutral controls

AM Pivirotto, A Platt, R Patel, S Kumar, J Hey - bioRxiv, 2023 - biorxiv.org
A classic population genetic prediction is that alleles experiencing directional selection
should swiftly traverse allele frequency space, leaving detectable reductions in genetic …

Germline genetic variants of the renin-angiotensin system, hypoxia and angiogenesis in non-small cell lung cancer progression: Discovery and validation studies

MJ Catarata, R Medeiros, MJ Oliveira, A Pêgo… - Cancers, 2020 - mdpi.com
Simple Summary The presence of polymorphic gene variants in the human genome
provides extensive genetic (and eventually phenotypic) variation affecting both normal …