AMD is a major cause of legal blindness in older adults approachable through
multidisciplinary research involving human tissues and patients. AMD is a vascular …

The interstitium describes the fluid, proteins, solutes, and the extracellular matrix (ECM) that
comprise the cellular microenvironment in tissues. Its alterations are fundamental to …

Purpose: This study aims to introduce and clinically validate a new algorithm that can
determine the biomechanical properties of the human cornea in vivo. Methods: A parametric …

Purpose To examine whether slowed rod-mediated dark adaptation (DA) in adults with
normal macular health at baseline is associated with the incidence of age-related macular …

Interstitial flow plays important roles in the morphogenesis, function, and pathogenesis of
tissues. To investigate these roles and exploit them for tissue engineering or to overcome …

Purpose.: The mechanical properties of corneal tissue are linked to prevalent ocular
diseases and therapeutic procedures. Brillouin microscopy is a novel optical technology that …

Acoustically induced inelastic light scattering, first reported in 1922 by Brillouin, allows non-
contact, direct readout of the viscoelastic properties of a material and has widely been …

Ageing is the largest risk factor for age-related macular degeneration (AMD), and soft drusen
and basal linear deposits are lipid-rich extracellular lesions specific to AMD. Oil red O …

Owing to the variety and complexity of ocular diseases and the natural ocular barriers, drug
therapy for ocular diseases has significant limitations, such as poor drug targeting to the site …

Biomaterials for corneal tissue engineering must demonstrate several critical features for
potential utility in vivo, including transparency, mechanical integrity, biocompatibility and …