Control of Mycobacterium tuberculosis (Mtb) infection requires generation of T cells that
migrate to granulomas, complex immune structures surrounding sites of bacterial replication …

Tuberculosis (TB), caused by infection with Mycobacterium tuberculosis (M. tb), is
responsible for> 1.5 million deaths worldwide annually. Innate immune cells, especially …

Infectious disease is the result of interactions between host and pathogen and can depend
on genetic variations in both. We conduct a genome-to-genome study of paired human and …

Efforts are underway globally to develop effective vaccines and drugs against M.
tuberculosis (Mtb) to reduce the morbidity and mortality of tuberculosis. Improving detection …

Abstract The ALDH2* 2 (rs671) allele is one of the most common genetic mutations in
humans, yet the positive evolutionary selective pressure to maintain this mutation is …

Tuberculosis caused by Mycobacterium tuberculosis (M. tb) is one of the main causes of
human death in the world. Bacillus Calmette‐Guérin (BCG) provides limited protection in …

Background Osteoporosis (OP) is a common metabolic bone disease characterized by loss
of bone mass. IL-10 is considered to be a powerful immune and inflammatory suppressor …

Rationale Lung mucins are an understudied component of the mucosal immune response
and may influence tuberculosis pathogenesis and outcomes. Objectives To assess if …

ABSTRACT Background and Objective: Dengue fever (DF) has been a major health concern
globally. Pakistan is also combating this infection for the last decade. Cytokine genes play …

Tuberculosis (TB), caused by infection with Mycobacterium tuberculosis (M. tb), is
responsible for> 1.5 million deaths worldwide annually. Innate immune cells, especially …