Effects of physical exercise on cognitive functioning and wellbeing: biological and psychological benefits

L Mandolesi, A Polverino, S Montuori, F Foti… - Frontiers in …, 2018 - frontiersin.org
Much evidence shows that physical exercise (PE) is a strong gene modulator that induces
structural and functional changes in the brain, determining enormous benefit on both …

Neurobiology of BDNF in fear memory, sensitivity to stress, and stress-related disorders

M Notaras, M van den Buuse - Molecular psychiatry, 2020 - nature.com
Brain-derived neurotrophic factor (BDNF) is widely accepted for its involvement in resilience
and antidepressant drug action, is a common genetic locus of risk for mental illnesses, and …

The role of the epididymis and the contribution of epididymosomes to mammalian reproduction

ER James, DT Carrell, KI Aston, TG Jenkins… - International Journal of …, 2020 - mdpi.com
It is well-established that testicular spermatozoa are immature and acquire motility and
fertilization capabilities during transit throughout the epididymis. The epididymis is a duct …

Adolescence and the next generation

GC Patton, CA Olsson, V Skirbekk, R Saffery… - Nature, 2018 - nature.com
Adolescent growth and social development shape the early development of offspring from
preconception through to the post-partum period through distinct processes in males and …

Physical exercise as an epigenetic modulator of brain plasticity and cognition

J Fernandes, RM Arida, F Gomez-Pinilla - Neuroscience & Biobehavioral …, 2017 - Elsevier
A large amount of evidence has demonstrated the power of exercise to support cognitive
function, the effects of which can last for considerable time. An emerging line of scientific …

Epigenetic inheritance: concepts, mechanisms and perspectives

I Lacal, R Ventura - Frontiers in molecular neuroscience, 2018 - frontiersin.org
Parents' stressful experiences can influence an offspring's vulnerability to many pathological
conditions, including psychopathologies, and their effects may even endure for several …

How does epigenetics influence the course of evolution?

A Ashe, V Colot, BP Oldroyd - … transactions of the …, 2021 - royalsocietypublishing.org
Epigenetics is the study of changes in gene activity that can be transmitted through cell
divisions but cannot be explained by changes in the DNA sequence. Epigenetic …

Transfer RNA-derived fragments and tRNA halves: biogenesis, biological functions and their roles in diseases

Y Shen, X Yu, L Zhu, T Li, Z Yan, J Guo - Journal of Molecular Medicine, 2018 - Springer
The number of studies on non-coding RNAs has increased substantially in recent years
owing to their importance in gene regulation. However, the biological functions of small …

Angiogenin mediates paternal inflammation-induced metabolic disorders in offspring through sperm tsRNAs

Y Zhang, L Ren, X Sun, Z Zhang, J Liu, Y Xin… - Nature …, 2021 - nature.com
Paternal environmental inputs can influence various phenotypes in offspring, presenting
tremendous implications for basic biology and public health and policy. However, which …

Priming for life: early life nutrition and the microbiota-gut-brain axis

A Ratsika, MC Codagnone, S O'Mahony, C Stanton… - Nutrients, 2021 - mdpi.com
Microbes colonize the human body during the first moments of life and coexist with the host
throughout the lifespan. Intestinal microbiota and their metabolites aid in the programming of …