In vitro Analytical Techniques as Screening Tools to investigate the Metal chelate‐DNA interactions

N Varghese, JR Jose, PM Krishna, D Philip… - …, 2023 - Wiley Online Library
Deoxyribose nucleic acid (DNA) is found to be the most efficient pharmacological target of
many synthetic molecules which are deemed as potential drugs with clinical applications …

Impact of aliphatic acyl and aromatic thioamide substituents on the anticancer activity of Ru (ii)-p-cymene complexes with acylthiourea ligands—in vitro and in vivo …

S Swaminathan, J Haribabu, MKM Subarkhan… - Dalton …, 2021 - pubs.rsc.org
Six different acylthiourea ligands (L1–L6) and their corresponding Ru (II)-p-cymene
complexes (P1–P6) were designed to explore the structure–activity relationship of the …

Synthesis of palladium (II) complexes via Michael addition: antiproliferative effects through ROS-mediated mitochondrial apoptosis and docking with SARS-CoV-2

J Haribabu, S Srividya, D Mahendiran… - Inorganic …, 2020 - ACS Publications
Metal complexes have numerous applications in the current era, particularly in the field of
pharmaceutical chemistry and catalysis. A novel synthetic approach for the same is always a …

[HTML][HTML] Schiff base metal complexes: Synthesis, optoelectronic, biological studies, fabrication of zinc oxide nanoparticles and its photocatalytic activity

P Mahadevi, S Sumathi - Results in Chemistry, 2023 - Elsevier
A Schiff base ligand from amino acid (L-Histidine) and salicylaldehyde (L1), 1, 10
phenanthroline (L2) and its transition metal complexes of general formula [ML1L2](where …

N-substitution in isatin thiosemicarbazones decides nuclearity of Cu (II) complexes–Spectroscopic, molecular docking and cytotoxic studies

J Haribabu, OI Alajrawy, K Jeyalakshmi… - … Acta Part A: Molecular …, 2021 - Elsevier
Abstract The mono-(1) and bi-nuclear (2) copper (II) complexes containing N-substituted
isatin thiosemicarbazone (s) were synthesized, and characterized by analytical and …

Mixed-ligand copper (II) Schiff base complexes: the vital role of co-ligands in DNA/protein interactions and cytotoxicity

S Kathiresan, S Mugesh, J Annaraj… - New Journal of …, 2017 - pubs.rsc.org
A series of four new mixed-ligand copper (II) complexes (1–4) of the type [Cu
(L)(diimine)](ClO4)[where L is 2-((1H-imidazol-2-yl) methylene)-N …

Synthesis and crystal structure of new monometallic and bimetallic copper (II) complexes with N-substituted isatin thiosemicarbazone ligands: Effects of the complexes …

M Muralisankar, S Sujith, NSP Bhuvanesh… - Polyhedron, 2016 - Elsevier
A novel series of N-substituted isatin thiosemicarbazone ligands (L1–L3) and their copper
(II) complexes [Cu (II)(ITSC)] were synthesized and characterized by elemental analyses …

Developing novel zinc (ii) and copper (ii) Schiff base complexes: combined experimental and theoretical investigation on their DNA/protein binding efficacy and …

M Das, S Mukherjee, B Koley, I Choudhuri… - New Journal of …, 2020 - pubs.rsc.org
Two new metal complexes, namely,[Zn2 (LH) 2 (N3) 4](1) and [Cu (L)(N3)](2), have been
derived from a Schiff base ligand,(E)-2-(((2-(piperidine-2-yl) ethyl) imino) methyl) phenol …

Synthesis of Ni (II) complexes bearing indole-based thiosemicarbazone ligands for interaction with biomolecules and some biological applications

J Haribabu, K Jeyalakshmi, Y Arun… - JBIC Journal of …, 2017 - Springer
A series of new Ni (II) complexes containing indole-based thiosemicarbazone ligands was
synthesized and characterized by elemental analyses, and UV–visible, FT-IR, 1 H & 13 C …

Investigation on bovine serum albumin (BSA) binding efficiency and antibacterial activity of ZnO nanoparticles

AR Prasad, SM Basheer, IR Gupta, KK Elyas… - Materials Chemistry and …, 2020 - Elsevier
Biomolecule-NPs interaction is extremely important in various biomedical applications
especially for assessing the macrostructural effects of nanoparticles on proteins. We …