Shining new light on biological systems: luminescent transition metal complexes for bioimaging and biosensing applications

LCC Lee, KKW Lo - Chemical Reviews, 2024 - ACS Publications
Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …

Fifty Shades of Phenanthroline: Synthesis Strategies to Functionalize 1, 10-Phenanthroline in All Positions

C Queffélec, PB Pati, Y Pellegrin - Chemical Reviews, 2024 - ACS Publications
1, 10-Phenanthroline (phen) is one of the most popular ligands ever used in coordination
chemistry due to its strong affinity for a wide range of metals with various oxidation states. Its …

Outpacing conventional nicotinamide hydrogenation catalysis by a strongly communicating heterodinuclear photocatalyst

L Zedler, P Wintergerst, AK Mengele, C Müller… - Nature …, 2022 - nature.com
Unequivocal assignment of rate-limiting steps in supramolecular photocatalysts is of utmost
importance to rationally optimize photocatalytic activity. By spectroscopic and catalytic …

A long-lived luminogenic iridium (III) complex for acetylacetone detection in environmental samples

W Wang, TL Yung, SS Cheng, F Chen, JB Liu… - Sensors and Actuators B …, 2020 - Elsevier
The wide use of acetylacetone (Acac) in industries is fueling the need for the development of
Acac detection methods. However, only a few nanomaterial-based fluorescent probes for …

A hexa-rhodium metallopeptide catalyst for site-specific functionalization of natural antibodies

J Ohata, ZT Ball - Journal of the American Chemical Society, 2017 - ACS Publications
Preparation of antibody–drug conjugates (ADCs), an emerging novel class of highly
targeted biological hybrid agents, necessitates precise control of conjugation reactivity …

Photoluminescence lifetime imaging of synthesized proteins in living cells using an Iridium–Alkyne probe

J Wang, J Xue, Z Yan, S Zhang, J Qiao… - Angewandte Chemie …, 2017 - Wiley Online Library
Designing probes for real‐time imaging of dynamic processes in living cells is a continuous
challenge. Herein, a novel near‐infrared (NIR) photoluminescence probe having a long …

A click chemistry approach to developing molecularly targeted DNA scissors

T Lauria, C Slator, V McKee, M Müller… - … A European Journal, 2020 - Wiley Online Library
Nucleic acid click chemistry was used to prepare a family of chemically modified triplex
forming oligonucleotides (TFOs) for application as a new gene‐targeted technology. Azide …

Labelling proteins and peptides with phosphorescent d6 transition metal complexes

TU Connell, PS Donnelly - Coordination Chemistry Reviews, 2018 - Elsevier
The phosphorescent properties of Ru (II), Re (I) and Ir (III) transition metal complexes, each
with a nominal d 6 electron configuration, are well suited to label peptides and proteins to …

Cationic Amphiphilic Tris-Cyclometalated Iridium(III) Complexes Induce Cancer Cell Death via Interaction with Ca2+-Calmodulin Complex

Y Hisamatsu, N Suzuki, AA Masum… - Bioconjugate …, 2017 - ACS Publications
In our previous paper, we reported on the preparation of some cationic amphiphilic Ir
complexes (2c, 2d) containing KKGG peptides that induce and detect cell death of Jurkat …

A dual-functional luminescent probe for imaging H2S in living zebrafish and discrimination hypoxic cells from normoxic cells

W Wang, C Wu, C Yang, G Li, QB Han, S Li… - Sensors and Actuators B …, 2018 - Elsevier
In this work, we present a new reaction-based luminogenic probe with dual functions: a
highly selective sensor for both in vitro H 2 S sensing and in vivo H 2 S imaging in living …