Recent human and animal model experimental studies revealed novel pathways for fluid
movement, immune cell trafficking and metabolic waste clearance in CNS. These studies …

Fluid homeostasis is fundamental for brain function with cerebral edema and hydrocephalus
both being major neurological conditions. Fluid movement from blood into brain is one …

Objective Choroid plexus (CP) is a key regulator in cerebrospinal fluid production, but its
contribution to glymphatic clearance function and association with white matter …

One of the pathological hallmarks of Alzheimer's and related diseases is the increased
accumulation of protein amyloid-β in the brain parenchyma. As such, recent studies have …

Background The choroid plexus functions as the blood-cerebrospinal fluid (CSF) barrier,
plays an important role in CSF production and circulation, and has gained increased …

ChP imaging metrics are emerging as possible biomarkers of neuroinflammation and repair
failure in MS. Future works combining multimodal imaging techniques should provide a …

Progress made by the medical community in increasing lifespans comes with the costs of
increasing the incidence and prevalence of age-related diseases, neurodegenerative ones …

Investigation of the choroid plexus in schizophrenia has seen growing interest due to its role
in the interaction between neuroinflammation and brain dysfunction. Most previous studies …

Objective Investigations of cerebrospinal fluid (CSF) flow aberrations in Huntington's
disease (HD) are of growing interest, as impaired CSF flow may contribute to mutant …

Background The dysregulation of the gut-brain axis in chronic inflammatory bowel diseases
can cause neuro-psychological disturbances, but the underlying mechanisms are still not …