The review demonstrates that control of posture and locomotion is provided by systems
across the caudal-to-rostral extent of the neuraxis. A common feature of the neuroanatomic …

Preclinical and clinical neurophysiological and neurorehabilitation research has generated
rather surprising levels of recovery of volitional sensory-motor function in persons with …

Epidural spinal cord stimulation (SCS) is currently regarded as a breakthrough procedure for
enabling movement after spinal cord injury (SCI), yet one of its original applications was for …

Neuronal hyperexcitability is a key element of many neurodegenerative disorders including
the motor neuron disease Amyotrophic Lateral Sclerosis (ALS), where it occurs associated …

Amyotrophic lateral sclerosis (ALS) is a fatal paralytic disorder caused by dysfunction and
degeneration of motor neurons. Multiple disease-causing mutations, including in the genes …

The low-threshold L-type calcium channel Cav1. 3 accelerates the pacemaker rate in the
heart, but its functional role for the extended dynamic range of neuronal firing is still …

Amyotrophic lateral sclerosis (ALS) is a devastating paralytic disorder caused by dysfunction
and degeneration of motoneurons starting in adulthood. Recent studies using cell or animal …

Amyotrophic lateral sclerosis (ALS) is the most common motor neuron (MN) disease and is
clinically characterised by the death of corticospinal motor neurons (CSMNs), spinal and …

Amyotrophic lateral sclerosis (ALS) is an adult-onset, lethal, paralytic disorder caused by the
degeneration of motor neurons. Our understanding of this disease has been greatly …

Delayed onset muscle soreness (DOMS) is hypothesized to be caused by glutamate
excitotoxicity-induced acute compression axonopathy of the sensory afferents in the muscle …