Baculovirus as versatile vectors for protein expression in insect and mammalian cells

TA Kost, JP Condreay, DL Jarvis - Nature biotechnology, 2005 - nature.com
Today, many thousands of recombinant proteins, ranging from cytosolic enzymes to
membrane-bound proteins, have been successfully produced in baculovirus-infected insect …

Baculovirus as a highly efficient expression vector in insect and mammalian cells

Y HU - Acta Pharmacologica Sinica, 2005 - Wiley Online Library
Baculovirus has been widely used for the production of recombinant proteins in insect cells.
Since the finding that baculovirus can efficiently transduce mammalian cells, the …

Cellular binding of hepatitis C virus envelope glycoprotein E2 requires cell surface heparan sulfate

H Barth, C Schäfer, MI Adah, F Zhang… - Journal of Biological …, 2003 - ASBMB
The conservation of positively charged residues in the N terminus of the hepatitis C virus
(HCV) envelope glycoprotein E2 suggests an interaction of the viral envelope with cell …

[HTML][HTML] HCV genome and life cycle

S Chevaliez, JM Pawlotsky - Hepatitis C viruses: genomes and …, 2006 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) infection afflicts more than 170 million people worldwide, with the
great majority of patients with acute hepatitis C developing chronic HCV infection. It can …

[HTML][HTML] Cell entry of hepatitis C virus

B Bartosch, FL Cosset - Virology, 2006 - Elsevier
Hepatitis C virus (HCV), an important human pathogen, is an enveloped, positive-stranded
RNA virus classified in the hepacivirus genus of the Flaviviridae family. Cell attachment of …

Assembly of human severe acute respiratory syndrome coronavirus-like particles

Y Ho, PH Lin, CYY Liu, SP Lee, YC Chao - Biochemical and biophysical …, 2004 - Elsevier
Viral particles of human severe acute respiratory syndrome coronavirus (SARS CoV) consist
of three virion structural proteins, including spike protein, membrane protein, and envelope …

Insect cells as a production platform of complex virus-like particles

F Fernandes, AP Teixeira, N Carinhas… - Expert review of …, 2013 - Taylor & Francis
Virus-like particles (VLPs) are multiprotein structures that resemble the conformation of
native viruses but lack a viral genome, potentiating their application as safer and cheaper …

Uptake and presentation of hepatitis C virus–like particles by human dendritic cells

H Barth, A Ulsenheimer, GR Pape, HM Diepolder… - Blood, 2005 - ashpublications.org
Hepatitis C virus (HCV) is a major cause of chronic hepatitis worldwide. Interaction of
dendritic cells (DCs) with viral particles may play an important role in the …

Hepatitis C virus viremia in HIV-infected individuals with negative HCV antibody tests

SL George, J Gebhardt, D Klinzman… - JAIDS Journal of …, 2002 - journals.lww.com
Hepatitis C virus (HCV) viremia may occur in persons without detectable HCV antibodies
and has been reported in as many as 5.5% of HIV-positive persons. To better characterize …

Down-regulation of heme oxygenase-1 by hepatitis C virus infection in vivo and by the in vitro expression of hepatitis C core protein

MY Abdalla, BE Britigan, F Wen, M Icardi… - The Journal of …, 2004 - academic.oup.com
Antioxidant enzymes, including heme oxygenase (HO)-1, are an important line of defense
against oxidant-mediated liver injury. Because hepatitis C virus (HCV) infection appears to …