Strategies for extending the half-life of biotherapeutics: successes and complications
U Binder, A Skerra - Expert Opinion on Biological Therapy, 2025 - Taylor & Francis
Introduction Engineering of the drug half-life in vivo has become an integral part of modern
biopharmaceutical development due to the fact that many proteins/peptides with therapeutic …
biopharmaceutical development due to the fact that many proteins/peptides with therapeutic …
[HTML][HTML] Intragland Expression of the Shh Gene Alleviates Irradiation-Induced Salivary Gland Injury through Microvessel Protection and the Regulation of Oxidative …
M Hu, L Hu, T Yang, B Zhou, X Feng, Z Fan, Z Shan - Antioxidants, 2024 - mdpi.com
Radiation-induced salivary gland injury (RISGI) is a common complication of radiotherapy in
patients with head and neck cancer. Intragland expression of the Sonic Hedgehog (Shh) …
patients with head and neck cancer. Intragland expression of the Sonic Hedgehog (Shh) …
[HTML][HTML] The Ability of Clinically Relevant Chemotherapeutics to Induce Immunogenic Cell Death in Squamous Cell Carcinoma
Z He, X Jing, X Dai, L Bao, X Yang… - Frontiers in Bioscience …, 2024 - imrpress.com
Background: Immunogenic cell death (ICD) is a crucial mechanism for triggering the
adaptive immune response in cancer patients. Damage-associated molecular patterns …
adaptive immune response in cancer patients. Damage-associated molecular patterns …