Paracetamol use during pregnancy—a call for precautionary action

AZ Bauer, SH Swan, D Kriebel, Z Liew… - Nature Reviews …, 2021 - nature.com
Abstract Paracetamol (N-acetyl-p-aminophenol (APAP), otherwise known as
acetaminophen) is the active ingredient in more than 600 medications used to relieve mild to …

Anogenital distance as a toxicological or clinical marker for fetal androgen action and risk for reproductive disorders

CL Schwartz, S Christiansen, AM Vinggaard… - Archives of …, 2019 - Springer
Male reproductive development is intricately dependent on fetal androgen action.
Consequently, disrupted androgen action during fetal life can interfere with the development …

Androgens and the masculinization programming window: human–rodent differences

RM Sharpe - Biochemical Society Transactions, 2020 - portlandpress.com
Human male reproductive disorders are common and may have a fetal origin—the testicular
dysgenesis syndrome (TDS) hypothesis. In rats, experimentally induced TDS disorders …

[HTML][HTML] Endocrine disruptors and the male reproductive system

JB Stukenborg, RT Mitchell, O Söder - Best Practice & Research Clinical …, 2021 - Elsevier
In recent years, there has been an increased incidence in several of the most common
reproductive disorders, including hypospadias and cryptorchidism in newborns, and …

[HTML][HTML] Experimentally induced testicular dysgenesis syndrome originates in the masculinization programming window

S van den Driesche, KR Kilcoyne, I Wagner… - JCI insight, 2017 - ncbi.nlm.nih.gov
The testicular dysgenesis syndrome (TDS) hypothesis, which proposes that common
reproductive disorders of newborn and adult human males may have a common fetal origin …

Over-the-counter analgesics during pregnancy: a comprehensive review of global prevalence and offspring safety

A Zafeiri, RT Mitchell, DC Hay… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Analgesia during pregnancy is often necessary. Due to their widespread
availability, many mothers opt to use over-the-counter (OTC) analgesics. Those analgesic …

The main changes in pregnancy—therapeutic approach to musculoskeletal pain

F Fiat, PE Merghes, AD Scurtu, B Almajan Guta… - Medicina, 2022 - mdpi.com
Background and Objectives: During pregnancy, women undergo various physiological and
anatomical changes that are accentuated as the pregnancy progresses, but return to their …

Ibuprofen results in alterations of human fetal testis development

M Ben Maamar, L Lesné, K Hennig… - Scientific reports, 2017 - nature.com
Among pregnant women ibuprofen is one of the most frequently used pharmaceutical
compounds with up to 28% reporting use. Regardless of this, it remains unknown whether …

A review on pharmaceuticals and personal care products residues in the aquatic environment and possibilities for their remediation

U Wydro, E Wołejko, L Luarasi, K Puto, Ž Tarasevičienė… - Sustainability, 2023 - mdpi.com
Pharmaceuticals and Personal Care Products (PPCPs) are pollutants known as organic
micropollutants. PPCPs belong to a group of compounds with proven biological activity used …

The relationship of prenatal acetaminophen exposure and attention-related behavior in early childhood

ML Woodbury, SD Geiger, SL Schantz - Neurotoxicology and teratology, 2024 - Elsevier
Acetaminophen is currently the only analgesic considered safe for use throughout
pregnancy, but recent studies indicate that prenatal exposure to acetaminophen may be …