RACK1, A multifaceted scaffolding protein: Structure and function

DR Adams, D Ron, PA Kiely - Cell communication and signaling, 2011 - Springer
Abstract The Receptor for Activated C Kinase 1 (RACK1) is a member of the tryptophan-
aspartate repeat (WD-repeat) family of proteins and shares significant homology to the β …

14-3-3 proteins in the nervous system

D Berg, C Holzmann, O Riess - Nature Reviews Neuroscience, 2003 - nature.com
3-3 proteins are abundantly expressed in the brain and have been detected in the
cerebrospinal fluid of patients with different neurological disorders. Although the function of …

14-3-3 proteins in brain development: neurogenesis, neuronal migration and neuromorphogenesis

B Cornell, K Toyo-Oka - Frontiers in molecular neuroscience, 2017 - frontiersin.org
The 14-3-3 proteins are a family of highly conserved, multifunctional proteins that are highly
expressed in the brain during development. Cumulatively, the seven 14-3-3 isoforms make …

14-3-3 Proteins—a focus on cancer and human disease

E Wilker, MB Yaffe - Journal of molecular and cellular cardiology, 2004 - Elsevier
14-3-3 Proteins are a ubiquitous family of molecules that participate in protein kinase
signaling pathways within all eukaryotic cells. Functioning as phosphoserine …

An atypical deletion of the Williams–Beuren syndrome interval implicates genes associated with defective visuospatial processing and autism

L Edelmann, A Prosnitz, S Pardo, J Bhatt… - Journal of medical …, 2007 - jmg.bmj.com
Background: During a genetic study of autism, a female child who met diagnostic criteria for
autism spectrum disorder, but also exhibited the cognitive–behavioural profile (CBP) …

RACK1 has the nerve to act: structure meets function in the nervous system

EH Sklan, E Podoly, H Soreq - Progress in neurobiology, 2006 - Elsevier
The receptor for activated protein kinase C 1 (RACK1) is an intracellular adaptor protein.
Accumulating evidence attributes to this member of the tryptophan-aspartate (WD) repeat …

A dual role for poly‐ADP‐ribosylation in spatial memory acquisition after traumatic brain injury in mice involving NAD+ depletion and ribosylation of 14‐3‐3γ

MA Satchell, X Zhang, PM Kochanek… - Journal of …, 2003 - Wiley Online Library
Abstract Poly (ADP‐ribose) polymerase‐1 (PARP‐1) is a homeostatic enzyme that
paradoxically contributes to disturbances in spatial memory acquisition after traumatic brain …

Proteomics in brain research: potentials and limitations

G Lubec, K Krapfenbauer, M Fountoulakis - Progress in Neurobiology, 2003 - Elsevier
The advent of proteomics techniques has been enthusiastically accepted in most areas of
biology and medicine. In neuroscience, a host of applications was proposed ranging from …

[HTML][HTML] Emerging roles of 14-3-3γ in the brain disorder

E Cho, JY Park - BMB reports, 2020 - ncbi.nlm.nih.gov
3-3 proteins are mostly expressed in the brain and are closely involved in numerous brain
functions and various brain disorders. Among the isotypes of the 14-3-3 proteins, 14-3-3γ is …

Disturbance of redox homeostasis in Down Syndrome: Role of iron dysmetabolism

E Barone, A Arena, E Head, DA Butterfield… - Free Radical Biology and …, 2018 - Elsevier
Down Syndrome (DS) is the most common genetic form of intellectual disability that leads in
the majority of cases to development of early-onset Alzheimer-like dementia (AD). The …