PRNCR1: a long non-coding RNA with a pivotal oncogenic role in cancer

A Bardhan, A Banerjee, K Basu, DK Pal, A Ghosh - Human genetics, 2022 - Springer
Long non-coding RNAs (lncRNAs) have been gaining importance in the field of cancer
research in recent years. PRNCR1 (prostate cancer-associated non-coding RNA1) is a 12.7 …

Circular RNAs as diagnostic biomarkers for gastric cancer: A comprehensive update from emerging functions to clinical significances

CY Xu, XX Zeng, LF Xu, M Liu, F Zhang - Frontiers in Genetics, 2022 - frontiersin.org
The incidence and mortality of gastric cancer ranks as a fouth leading cause of cancer death
worldwide, especially in East Asia. Due to the lack of specific early-stage symptoms, the …

[HTML][HTML] Long non-coding RNA HOTAIR induces the PI3K/AKT/mTOR signaling pathway in breast cancer cells

M Sadeghalvad, K Mansouri… - Revista da Associação …, 2022 - SciELO Brasil
SUMMARY OBJECTIVE: The phosphoinositide 3-kinase/protein kinase AKT/mammalian
target of rapamycin signaling pathway is essential for proper cellular metabolism and cell …

A proposed TUSC7/miR-211/Nurr1 ceRNET might potentially be disturbed by a cer-SNP rs2615499 in breast cancer

R Abdollahzadeh, A Azarnezhad, S Paknahad… - Biochemical …, 2022 - Springer
Evidence and in silico analyses showed that TUSC7, miR-211, and Nurr1 may be involved
in BC pathogenesis by ceRNET signaling axis. This study aimed to investigate the potential …

Chimeric Antigen Receptor (CAR) T cell immunotherapy for solid tumors

A Esmaeilzadeh, D Jafari, R Elahi, M Bazargan… - 2023 - Springer
Chimeric antigen receptor (CAR) T cells are engineered T lymphocytes that redirect the
immune cell against a specific target antigen. As a novel immunotherapeutic method, CAR T …

A review on the role of PRNCR1 in human disorders with an especial focus on cancer

S Ghafouri-Fard, T Khoshbakht, BM Hussen… - … -Research and Practice, 2022 - Elsevier
Abstract Prostate Cancer Associated Non-Coding RNA 1 (PRNCR1) is a long non-coding
RNA (lncRNA) which is transcribed from chromosome 8, plus strand. This lncRNA has been …

Screening potential lncRNA biomarkers for breast cancer and colorectal cancer combining random walk and logistic matrix factorization

S Li, M Chang, L Tong, Y Wang, M Wang… - Frontiers in …, 2023 - frontiersin.org
Breast cancer and colorectal cancer are two of the most common malignant tumors
worldwide. They cause the leading causes of cancer mortality. Many researches have …

LincRNA PRNCR1 activates the Wnt/β-catenin pathway to drive the deterioration of hepatocellular carcinoma via regulating miR-411-3p/ZEB1 axis

P Zhou, Y Liu, G Wu, K Lu, T Zhao… - … and Genetic Engineering …, 2024 - Taylor & Francis
Hepatocellular carcinoma (HCC) is an intractable malignant disease with high incidence
rate annually. LincRNA PRNCR1 has been confirmed as a tumor supporter, while its …

[PDF][PDF] Unveiling the Prognostic Significance of Long Non-Coding RNA (lncRNA) PCAT1 in Invasive Breast Carcinoma

B Chakrabarty, K Afrin, S Islam, N Kundu… - Eurasian Journal of …, 2024 - researchgate.net
Objective: Prostate cancer-associated transcript 1 (PCAT1) is a long non-coding RNA
(lncRNA), composed of more than 200 nucleotides which expression controls the …

Immune Gene Therapy of Cancer

A Esmaeilzadeh, D Jafari, M Ghaebi, R Elahi… - Handbook of Cancer …, 2023 - Springer
Cancer is the second global cause of mortality. Conventional treatments, such as
chemotherapy and radiotherapy, have not provided desirable responses, and therefore …