Type 2 diabetes mellitus (T2DM), a disease on the rise and with huge economic burden to
health care systems around the globe, results from defects in insulin action (termed insulin …

Abstract New annulated pyrano [2, 3-d] pyrimidine derivatives were synthesized with
hydroxyl, methoxy, bromine, nitrile and nitro substituents on its skeleton. The correlated …

Inflammation, oxidation, and compromised immunity all increase the dangers of COVID-19,
whereas many pharmaceutical protocols may lead to increased immunity such as ingesting …

Diabetes is a wide spread systemic disease affecting a significant proportion of the
population worldwide. There is increasing evidence that increased production and/or …

Excess production of reactive oxygen species and the loss of antioxidant efficiency systems
play an important role in the development of diabetes. Thus, using antioxidant compounds is …

Abstract Eight new 7-substituted quinolin-8-ol derivatives were synthesized in moderate to
good yields through quinolin-8-ol, and secondary amines as the starting reagents. The …

Abstract The 1, 3-dipolar cycloaddition of nitrile imines to 11-aryl-4-(arylmethylidene)-1, 2, 3,
4, 11, 11a-hexahydrodibenzo [b, e][1, 4] thiazepines possessing exocyclic C= C and …

Background: The function of Carbonic anhydrase is to facilitate the physiological process ie
interconversion of CO2 to HCO3-by hydration. Carbonic anhydrase enzyme plays a vital role …

Moroccan flora, renowned for its diverse medicinal plant species, has long been used in
traditional medicine to manage diabetes. This review synthesizes ethnobotanical surveys …

POM analysis and computational interactions of 8-hydroxydiospyrin inside active site of
protein tyrosine phosphatase 1B Page 1 POM analysis and computational interactions of 8-hydroxydiospyrin …