Cytoplasmic vacuolization (also called cytoplasmic vacuolation) is a well-known
morphological phenomenon observed in mammalian cells after exposure to bacterial or viral …

The field of mitochondrial ion channels has recently seen substantial progress, including the
molecular identification of some of the channels. An integrative approach using genetics …

Zingerone (ZO), an active phenolic agent derived from Zingiber officinale (Ginger), has many
pharmacological properties such as antioxidant, antiangiogenic, and antitumor. However, its …

We recently reported that shikonin and its analogs were a class of necroptotic inducers that
could bypass cancer drug resistance. However, the molecular targets of shikonin are not …

The bark and/or seed cones of the Magnolia tree have been used in traditional herbal
medicines in Korea, China and Japan. Bioactive ingredients such as magnolol, honokiol, 4 …

In spite of billions of dollars expended on cancer research every year, the incidence rate and
the mortality rate due to this widespread disease has increased drastically over the last few …

Cancer is characterised by uncontrolled cell division and abnormal cell growth, which is
largely caused by a variety of gene mutations. There are continuous efforts being made to …

Given the problems with malignant cancer cells showing innate and acquired resistance to
apoptosis, we need alternative means to induce cell death in cancer. Paraptosis is a type of …

Honokiol is a small-molecule polyphenol isolated from the genus Magnolia. It is
accompanied by other related polyphenols, including magnolol, with which it shares certain …

It has been reported that curcumin inhibited various types of cancer cells in vitro and in vivo.
However, mechanisms of curcumin-inhibited cell growth and-induced apoptosis in human …