During pregnancy, the mother must adapt her body systems to support nutrient and oxygen
supply for growth of the baby in utero and during the subsequent lactation. These include …

The placenta is the chief regulator of nutrient supply to the growing embryo during gestation.
As such, adequate placental function is instrumental for developmental progression …

Spatial transcriptomic techniques offer unprecedented insights into the molecular
organization of complex tissues. However, integrating cost-effectiveness, high throughput, a …

Since establishment of the first embryonic stem cells (ESCs), in vitro culture of totipotent cells
functionally and molecularly comparable with in vivo blastomeres with embryonic and …

Epidemiological evidence links an individual's susceptibility to chronic disease in adult life to
events during their intrauterine phase of development. Biologically this should not be …

The placenta is an ephemeral but critical organ for the survival of all eutherian mammals
and marsupials. It is the primary messenger system between the mother and fetus, where …

The placenta is the interface between mother and fetus in all eutherian species. However,
our understanding of this essential organ remains incomplete. A substantial challenge has …

Although much progress is being made in understanding the molecular pathways in the
placenta that are involved in the pathophysiology of pregnancy-related disorders, a …

The placenta is one of the organs with the highest evolutionary diversity among animal
species. In consequence, an animal model that reflects human placentation exactly does not …

The still apt definition of a placenta is that coined by Mossman, namely apposition or fusion
of the fetal membranes to the uterine mucosa for physiological exchange. As such it is a …