Lectins, interconnecting proteins with biotechnological/pharmacological and therapeutic applications

LCBB Coelho, PMS Silva, VLM Lima… - Evidence‐Based …, 2017 - Wiley Online Library
Lectins are proteins extensively used in biomedical applications with property to recognize
carbohydrates through carbohydrate‐binding sites, which identify glycans attached to cell …

Plant triterpenoid saponins: biosynthesis, in vitro production, and pharmacological relevance

T Biswas, UN Dwivedi - Protoplasma, 2019 - Springer
The saponins are a diverse class of natural products, with a broad scale distribution across
different plant species. Chemically characterized as triterpenoid glycosides, they posses a …

Bitter melon (Momordica charantia): a natural healthy vegetable

F Saeed, M Afzaal, B Niaz, MU Arshad… - … Journal of Food …, 2018 - Taylor & Francis
Bitter melon provides health benefits against various ailments for improving the quality of
life. It is nutrient dense plant-based food containing versatility of bioactive compounds such …

Promise of bitter melon (Momordica charantia) bioactives in cancer prevention and therapy

K Raina, D Kumar, R Agarwal - Seminars in cancer biology, 2016 - Elsevier
Recently, there is a paradigm shift that the whole food-derived components are not 'idle
bystanders' but actively participate in modulating aberrant metabolic and signaling pathways …

Plant Lectins Targeting O-Glycans at the Cell Surface as Tools for Cancer Diagnosis, Prognosis and Therapy

G Poiroux, A Barre, EJM Van Damme… - International journal of …, 2017 - mdpi.com
Aberrant O-glycans expressed at the surface of cancer cells consist of membrane-tethered
glycoproteins (T and Tn antigens) and glycolipids (Lewis a, Lewis x and Forssman …

[HTML][HTML] Current status of lectin-based cancer diagnosis and therapy

FS Coulibaly, BBC Youan - AIMS Molecular Science, 2017 - aimspress.com
Lectins are carbohydrate recognizing proteins originating from diverse origins in nature,
including animals, plants, viruses, bacteria and fungus. Due to their exceptional glycan …

[HTML][HTML] Exploring the phytochemistry, pharmacognostic properties, and pharmacological activities of medically important plant Momordica charantia

S Mukherjee, D Karati - Pharmacological Research-Modern Chinese …, 2023 - Elsevier
Abstract Background The World Health Organization describes traditional medicine as a
variation of health practises, approaches, knowledge, and beliefs that include manual …

Plant lectins as medical tools against digestive system cancers

LE Estrada-Martínez, U Moreno-Celis… - International journal of …, 2017 - mdpi.com
Digestive system cancers—those of the esophagus, stomach, small intestine, colon-rectum,
liver, and pancreas—are highly related to genetics and lifestyle. Most are considered highly …

Exploring the inhibitory potentials of Momordica charantia bioactive compounds against Keap1-Kelch protein using computational approaches

TI Adelusi, M Abdul-Hammed, MO Idris… - In Silico …, 2021 - Springer
The search for Keap1 inhibitors as potential Nrf2 activator is a way of increasing the
antioxidant status of the human cellular environ. In this research, we used in silico methods …

Moringa oleifera seed lectin inhibits Ehrlich ascites carcinoma cell growth by inducing apoptosis through the regulation of Bak and NF-κB gene expression

AKM Asaduzzaman, I Hasan, A Chakrabortty… - International journal of …, 2018 - Elsevier
A Moringa oleifera seed lectin (MOSL) was purified by using chitin column with the
molecular mass of 17±1 kDa. The lectin agglutinated mouse, cow and human erythrocytes …