Many research questions in fields such as personalized medicine, drug screens or systems
biology depend on obtaining consistent and quantitatively accurate proteomics data from …

In the era of quantitative proteomics, where mass spectrometry plays a pivotal role, in
particular associated with the use of data‐independent acquisition, it is time to perform an …

Human blood plasma provides a highly accessible window to the proteome of any individual
in health and disease. Since its inception in 2002, the Human Proteome Organization's …

Introduction: While selected/multiple-reaction monitoring (SRM or MRM) is considered the
gold standard for quantitative protein measurement, emerging data-independent acquisition …

Data-independent acquisition (DIA) mass spectrometry (MS) has emerged as a powerful
technology for high-throughput, accurate, and reproducible quantitative proteomics. This …

Most applied proteomic approaches require labeling steps. Recent technological advances
provide an alternative label-free proteomics approach: SWATH-MS. This powerful tool is …

Data‐independent acquisition (DIA) is an emerging technology for quantitative proteomics.
Current DIA focusses on the identification and quantitation of fragment ions that are …

Consistent detection and quantification of protein post-translational modifications (PTMs)
across sample cohorts is a prerequisite for functional analysis of biological processes. Data …

Protein post‐translational modifications (PTMs) increase the functional diversity of the
cellular proteome. Accurate and high throughput identification and quantification of protein …

Post-translational modifications (PTMs) can occur soon after translation or at any stage in
the lifecycle of a given protein, and they may help regulate protein folding, stability, cellular …