Alzheimer's disease (AD) is a common neurodegenerative disorder with progressive
cognitive impairment in the elderly. Beta-amyloid (Aβ) formation and its accumulation in the …

Jumping translocation breakpoint (JTB) gene acts as a tumor suppressor or an oncogene in
different malignancies, including breast cancer (BC), where it was reported as …

Leishmania donovani, the causative agent of visceral leishmaniasis, infects and resides
within tissue macrophage cells. It is not clear how the parasite infected cells crosstalk with …

The intricate interplay between extracellular vesicles (EVs), microRNAs, and RNA binding
proteins (RBPs) constitutes a crucial mechanism in glioblastoma pathogenesis. The …

Intercellular miRNA exchange acts as a key mechanism to control gene expression post-
transcriptionally in mammalian cells. Regulated export of repressive miRNAs allows the …

Hepatocytes on exposure to high levels of lipids reorganize the metabolic program while
fighting against the toxicity associated with elevated cellular lipids. The mechanism of this …

Extracellular vesicles–mediated exchange of miRNA cargos between diverse types of
mammalian cells is a major mechanism of controlling cellular miRNA levels and activity, thus …

Leishmania donovani, the causative agent of visceral leishmaniasis, infects and resides
within tissue macrophage cells of the mammalian host. It is not clear how the parasite …

Regulated export of repressive miRNAs allows the expression of inflammatory cytokines in
activated macrophages. Intracellular trafficking of miRNAs to endosomes is a rate …

Small RNAs are an exciting class of therapeutics with significant untapped therapeutic
potential, due to their ability to affect cell behavior at the RNA level. However, delivery of …