Intrauterine growth restriction–part 1

D Sharma, S Shastri, N Farahbakhsh… - The journal of maternal …, 2016 - Taylor & Francis
Intrauterine growth restriction (IUGR) is a major and silent cause of various morbidity and
mortality for the fetal and neonatal population. It is defined as a rate of fetal growth that is …

Circulating microRNAs: Association with disease and potential use as biomarkers

G Reid, MB Kirschner, N van Zandwijk - Critical reviews in oncology …, 2011 - Elsevier
The control of gene expression by microRNAs influences many cellular processes and has
been implicated in the control of many (patho) physiological states. Recently, microRNAs …

Human placental trophoblasts confer viral resistance to recipient cells

E Delorme-Axford, RB Donker… - Proceedings of the …, 2013 - National Acad Sciences
Placental trophoblasts form the interface between the fetal and maternal environments and
serve to limit the maternal–fetal spread of viruses. Here we show that cultured primary …

MicroRNAs in human placental development and pregnancy complications

G Fu, J Brkić, H Hayder, C Peng - International journal of molecular …, 2013 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs, which function as critical
posttranscriptional regulators of gene expression by promoting mRNA degradation and …

The expression profile of C19MC microRNAs in primary human trophoblast cells and exosomes

RB Donker, JF Mouillet, T Chu, CA Hubel… - Molecular human …, 2012 - academic.oup.com
The largest gene cluster of human microRNAs (miRNAs), the chromosome 19 miRNA
cluster (C19MC), is exclusively expressed in the placenta and in undifferentiated cells. The …

Unique microRNA signals in plasma exosomes from pregnancies complicated by preeclampsia

H Li, Y Ouyang, E Sadovsky, WT Parks, T Chu… - …, 2020 - Am Heart Assoc
Although preeclampsia is a common and serious complication of pregnancy, insight into its
pathobiology and diagnosis is lacking. Circulating plasma exosomes, which contain RNA …

Gestational hypoxia and developmental plasticity

CA Ducsay, R Goyal, WJ Pearce… - Physiological …, 2018 - journals.physiology.org
Hypoxia is one of the most common and severe challenges to the maintenance of
homeostasis. Oxygen sensing is a property of all tissues, and the response to hypoxia is …

Pregnancy-associated miRNA-clusters

DM Morales-Prieto, S Ospina-Prieto… - Journal of reproductive …, 2013 - Elsevier
MicroRNAs (miRNAs) are expressed in the placenta and can be detected in maternal
plasma. An increasing number of studies have been published on the cellular origin …

MicroRNAs: crucial regulators of placental development

H Hayder, J O'Brien, U Nadeem, C Peng - Reproduction, 2018 - rep.bioscientifica.com
MicroRNAs (miRNAs) are small non-coding single-stranded RNAs that are integral to a wide
range of cellular processes mainly through the regulation of translation and mRNA stability …

Digital PCR analysis of circulating nucleic acids

I Hudecova - Clinical biochemistry, 2015 - Elsevier
Detection of plasma circulating nucleic acids (CNAs) requires the use of extremely sensitive
and precise methods. The commonly used quantitative real-time polymerase chain reaction …