Antibody therapy (as either active or passive immunization) is designed primarily to prevent
drugs of abuse from entering the central nervous system (CNS). Antidrug antibodies reduce …

A series of tobacco mosaic virus (TMV)-based hybrid vectors for transient gene expression
were constructed with similar designs but differing in the source of heterologous …

A tobacco mosaic virus (TMV)-based vector was utilized for expression of a cytosolic form of
the bovine herpesvirus type 1 (BHV-1) protein glycoprotein D (gDc). Nicotiana benthamiana …

A potential use of virus-based transient expression vectors is the large-scale production of
commercial specialty products, which would require the inoculation of many acres of plants …

The majority of viruses infecting higher plants have single-stranded, positive (or message-)
sense RNA genomes. Infectious transcripts can be synthesized in vitro from full-length cDNA …

We have previously reported on the use of a tobacco mosaic virus (TMV) vector TMV-30B to
express foreign viral antigens for use as experimental immunogens. Here we describe the …

It is now fairly routine to engage plant viruses to express foreign proteins in plants. Plant
viruses have several features that make them quite useful for vectoring foreign genes into …

Abstract Positive-strand (+) RNA plant viruses have genomes composed of messenger
sense RNA, and do not utilize a DNA intermediate in any stage of their life cycle …

The present invention relates to plant produced native aprotinin and aprotinin variants
having enzyme-inhibitory, immunological and pharmacokinetic properties and their …

The present invention relates to plant produced native apro tinin and aprotinin variants
having enzyme-inhibitory, immunological and pharmacokinetic properties and their …