Development of the Binary and Ternary Atorvastatin Solid Dispersions: In Vitro and In Vivo Investigations

E Faraji, M Mohammadi… - BioMed Research …, 2021 - Wiley Online Library
The object of this study was to prepare binary and ternary solid dispersions of atorvastatin
(ATR) by the melting method using PEGs and poloxamer 188 (P188) as the carriers, singly …

Physicochemical characteristics of the complexes of simvastatin and atorvastatin calcium with hydroxypropyl-β-cyclodextrin produced by mechanochemical activation

R Kong, X Zhu, ES Meteleva, AV Dushkin… - Journal of Drug Delivery …, 2018 - Elsevier
In the present work, inclusion complexes of simvastatin (SIM), atorvastatin calcium (ATV)
with hydroxypropyl-β-cyclodextrin (HP-β-CD) have been prepared using mechanochemistry …

Molecular dynamics and related solution chemistry of lovastatin in aqueous solution of arginine: Viscometric analysis

NF Zolkiflee, MMRMM Affandi, ABA Majeed - Journal of Molecular Liquids, 2019 - Elsevier
The solubility of lovastatin (LVS; solute) in water (solvent) is enhanced in the presence of
arginine (ARG) as the cosolute. Therefore, this current study was conducted to delve further …

Inclusion complexes of atorvastatin calcium (ATV‐Ca) and rosuvastatin calcium (ROV‐Ca) drugs with α‐CD, β‐CD, γ‐CD, HP‐β‐CD, M‐β‐CD, and maltodextrin …

A Ahmadi, M Ayoubi‐Chianeh… - … Canadian Journal of …, 2023 - Wiley Online Library
The aim of this research is a comparison of the efficiency of six commercially available
cyclodextrins (CDs) to improve the solubility and oral bioavailability of atorvastatin calcium …

Ultrasonic studies and acoustic parameters of complexes containing copper surfactants with 2-amino-6-methyl benzo-thiazole

AK Sharma, R Sharma… - Current Physical Chemistry, 2018 - ingentaconnect.com
Background: Ultrasonic speed and density parameters have been measured in binary and
ternary systems containing complexes of copper surfactants (caprylate, caprate, and laurate) …

[PDF][PDF] Study Of Physico-Chemical Properties Of Paracetamol As Pharmaceutical Waste In Water: An Analysis Of Molecular Interactions

M Talukdar, S Singh - Int. J. Sci. Tech. Res, 2020 - academia.edu
The presence of pharmaceutical wastes has been detected in various water environments.
These pharmaceutical pollutants may lead to serious problems to human and animal health …

[PDF][PDF] SISTEMAS LIQUISSÓLIDOS COMO UMA ABORDAGEM TECNOLÓGICA PARA MELHORAR O PERFIL DE DISSOLUÇÃO DA SINVASTATINA

D Anzilaggo - 2017 - core.ac.uk
RESUMO A baixa solubilidade aquosa de fármacos é um dos fatores que desafiam
pesquisadores no desenvolvimento de medicamentos. Os sistemas liquissólidos têm …