Recent trends in diagnostic biomarkers of tumor microenvironment

P Siminzar, MR Tohidkia, E Eppard, N Vahidfar… - Molecular Imaging and …, 2023 - Springer
The tumor microenvironment (TME) play critical roles in tumor survival, progression, and
metastasis and can be considered potential targets for molecular imaging of cancer. The …

18F FDG PET/CT and Novel Molecular Imaging for Directing Immunotherapy in Cancer

DJ Hughes, M Subesinghe, B Taylor, A Bille, J Spicer… - Radiology, 2022 - pubs.rsna.org
Immunotherapy has transformed the treatment landscape of many cancers, with durable
responses in disease previously associated with a poor prognosis. Patient selection remains …

Molecular imaging of innate immunity and immunotherapy

W Xia, N Singh, S Goel, S Shi - Advanced Drug Delivery Reviews, 2023 - Elsevier
The innate immune system plays a key role as the first line of defense in various human
diseases including cancer, cardiovascular and inflammatory diseases. In contrast to tissue …

The future of cancer diagnosis, treatment and surveillance: a systemic review on immunotherapy and immuno-pet radiotracers

V Liberini, R Laudicella, M Capozza, MW Huellner… - Molecules, 2021 - mdpi.com
Immunotherapy is an effective therapeutic option for several cancers. In the last years, the
introduction of checkpoint inhibitors (ICIs) has shifted the therapeutic landscape in oncology …

Emerging biomedical imaging-based companion diagnostics for precision medicine

S Liao, M Zhou, Y Wang, C Lu, B Yin, Y Zhang, H Liu… - Iscience, 2023 - cell.com
The tumor heterogeneity, which leads to individual variations in tumor microenvironments,
causes poor prognoses and limits therapeutic response. Emerging technology such as …

Positron emission tomography molecular imaging‐based cancer phenotyping

C Jin, X Luo, X Li, R Zhou, Y Zhong, Z Xu, C Cui… - Cancer, 2022 - Wiley Online Library
During the past several decades, numerous studies have provided insights into biological
characteristics of cancer cells and identified various hallmarks of cancer acquired in the …

Combinatorial immunotherapy with gemcitabine and ex vivo-expanded NK cells induces anti-tumor effects in pancreatic cancer

EK Koh, HR Lee, WC Son, GY Park, J Kim, JH Bae… - Scientific Reports, 2023 - nature.com
Pancreatic cancer is difficult to diagnose at the initial stage and is often discovered after
metastasis to nearby organs. Gemcitabine is currently used as a standard treatment for …

NKp30‐A prospective target for new cancer immunotherapy strategies

PF Pinheiro, GC Justino… - British Journal of …, 2020 - Wiley Online Library
Natural killer (NK) cells are an important arm of the innate immune system. They
constitutively express the NKp30 receptor. NKp30‐mediated responses are triggered by the …

[HTML][HTML] Cytogenetic and molecular aberrations and worse outcome for male patients in systemic mastocytosis

HC Kluin-Nelemans, M Jawhar, A Reiter… - Theranostics, 2021 - ncbi.nlm.nih.gov
In systemic mastocytosis (SM), the clinical features and survival vary greatly. Patient-related
factors determining the outcome in SM are largely unknown. Methods: We examined the …

In vivo cell tracking using PET: Opportunities and challenges for clinical translation in oncology

LM Lechermann, D Lau, B Attili, L Aloj, FA Gallagher - Cancers, 2021 - mdpi.com
Simple Summary Tracking therapeutic cells with non-invasive imaging methods has the
potential to provide important information on the efficacy of cell therapies. In oncology, for …