Methylation of arginine residues by protein arginine methyltransferases (PRMTs) is involved
in the regulation of fundamental cellular processes, including transcription, RNA processing …

Protein methylation, a post-translational modification (PTM), is observed in a wide variety of
cell types from prokaryotes to eukaryotes. With recent and rapid advancements in epigenetic …

Protein methyl transferases play critical roles in numerous regulatory pathways that underlie
cancer development, progression and therapy-response. Here we discuss the function of …

Post-translational modification (PTM) of proteins is vital for increasing proteome diversity
and maintaining cellular homeostasis. If the writing, reading, and removal of modifications …

Myosin phosphatase (MP) holoenzyme is a Ser/Thr specific enzyme, which is the member of
protein phosphatase type 1 (PP1) family and composed of a PP1 catalytic subunit …

Protein arginine methyltransferase (PRMT)-mediated arginine methylation is an important
post-transcriptional modification that regulates various cellular processes including …

Cancer is the second leading cause of death worldwide. Despite the availability of
numerous therapeutic options, tumor heterogeneity and chemoresistance have limited the …

DEP domain‑containing protein 1B (DEPDC1B) has been reported to serve important
functions in breast cancer and non‑small cell lung cancer. However, its involvement in the …

Hepatocellular carcinoma (HCC) is one of the most frequently diagnosed cancers with a
high mortality rate worldwide. The complexity of HCC initiation and progression poses a …

Among the widespread and increasing number of identified post-translational modifications
(PTMs), arginine methylation is catalyzed by the protein arginine methyltransferases …