Microbiological and antioxidant activity of phenolic compounds in olive leaf extract

D Borjan, M Leitgeb, Ž Knez, MK Hrnčič - Molecules, 2020 - mdpi.com
According to many reports, phenolic compounds isolated from olive leaves have very good
biological activities, especially antimicrobial. Presently, the resistance of microorganisms to …

Cardioprotective mechanisms of phytochemicals against doxorubicin-induced cardiotoxicity

AI Abushouk, A Ismail, AMA Salem, AM Afifi… - Biomedicine & …, 2017 - Elsevier
Doxorubicin (DOX) is an anthracycline antibiotic, which is effectively used in the treatment of
different malignancies, such as leukemias and lymphomas. Its most serious side effect is …

[HTML][HTML] Olea europaea leaf extract up-regulates Nrf2/ARE/HO-1 signaling and attenuates cyclophosphamide-induced oxidative stress, inflammation and apoptosis in …

HAS ALHaithloul, MF Alotaibi, M Bin-Jumah… - Biomedicine & …, 2019 - Elsevier
Olive leaf extract (OLE) has potential health benefits and protects against cytotoxicity in
different organs. However, nothing has yet been reported on its potential to prevent …

Luteolin attenuates doxorubicin-induced derangements of liver and kidney by reducing oxidative and inflammatory stress to suppress apoptosis

SE Owumi, DO Lewu, UO Arunsi… - Human & experimental …, 2021 - journals.sagepub.com
Doxorubicin is an effective anti-neoplastic agent; the reported toxicities of DOX limit its use.
Luteolin is a polyphenolic phytochemical that exhibits beneficial biological effects via …

Oleuropein suppresses oxidative, inflammatory, and apoptotic responses following glycerol-induced acute kidney injury in rats

M Yin, N Jiang, L Guo, Z Ni, AY Al-Brakati, MS Othman… - Life sciences, 2019 - Elsevier
Aim Here, we evaluated the possible protective effects of oleuropein, the major phenolic
constituent in virgin olive oil against glycerol-induced acute kidney injury (AKI) in rats. Main …

Combined chemo-magnetic field-photothermal breast cancer therapy based on porous magnetite nanospheres

M Sharifi, A Hasan, NMQ Nanakali, A Salihi… - Scientific Reports, 2020 - nature.com
The efficacy of different modalities of treating breast cancer is inhibited by several limitations
such as off-targeted drug distribution, rapid drug clearance, and drug resistance. To …

Polyphenolic-enriched olive leaf extract attenuated doxorubicin-induced cardiotoxicity in rats via suppression of oxidative stress and inflammation

AA Hamza, SO Hassanin, S Hamza, A Abdalla… - The Journal of Basic and …, 2021 - Springer
Background The therapeutic value of doxorubicin as an effective anti-neoplastic agent is
limited by its cardiotoxic side effects. We investigated the effects of ethanolic leaf extracts of …

p-Coumaric acid mitigates doxorubicin-induced nephrotoxicity through suppression of oxidative stress, inflammation and apoptosis

Z Rafiee, MZ Moaiedi, AV Gorji, E Mansouri - Archives of medical research, 2020 - Elsevier
Background and Aims P-Coumaric acid (PCA) is one the compound that has free radical
scavenging effects. This study investigates the protective effect of PCA on tissue damage in …

Antihypertensive effects of roselle‐olive combination in L‐NAME‐induced hypertensive rats

RF Abdel-Rahman, AF Hessin… - Oxidative medicine …, 2017 - Wiley Online Library
This study aimed to evaluate the antihypertensive efficacy of a new combination therapy of
Hibiscus sabdariffa and Olea europaea extracts (2: 1; Roselle‐Olive), using N (G)‐nitro‐L …

Systematic evaluations of doxorubicin-induced toxicity in rats based on metabolomics

C Geng, C Cui, C Wang, S Lu, M Zhang, D Chen… - ACS …, 2020 - ACS Publications
Doxorubicin (DOX) is widely used to treat solid tumors, but its use is limited by its severe
cardiotoxicity, nephrotoxicity, hepatotoxicity, and neurotoxicity. Metabolomic studies on DOX …