Synthetic biology allows us to reuse, repurpose, and reconfigure biological systems to
address society's most pressing challenges. Developing biotechnologies in this way …

Nanomanufacturing, the commercially scalable and economically sustainable mass
production of nanoscale materials and devices, represents the tangible outcome of the …

Understanding the folding process of DNA origami is a critical stepping stone to the broader
implementation of nucleic acid nanofabrication technology but is notably nontrivial. Origami …

We investigate the kinetics and thermodynamics of DNA origami dimerization using flat
rectangle origami components and different architectures of Watson–Crick complementary …

Macromolecular complexes are often composed of diverse subunits. The self-assembly of
these subunits is inherently nonequilibrium and must avoid kinetic traps to achieve high …

To optimize a self-assembly reaction, it is essential to understand the factors that govern its
pathway. Here, we examine the influence of nucleation pathways in a model system for …

We report Monte Carlo simulations of a simple off-lattice patchy-particle model for DNA
'bricks'. We relate the parameters that characterise this model with the binding free energy of …

While the self-assembly of different types of DNA origami into well-defined complexes could
produce nanostructures on which thousands of locations can be independently …

We report canonical and grand-canonical lattice Monte Carlo simulations of the self-
assembly of addressable structures comprising hundreds of distinct component types. The …

When chemically fueled, molecular self-assembly can sustain dynamic aggregates of
polymeric fibers—hydrogels—with tunable properties. If the fuel supply is finite, the hydrogel …