An old method facing a new challenge: re-visiting housekeeping proteins as internal reference control for neuroscience research

R Li, Y Shen - Life sciences, 2013 - Elsevier
The study of specific target protein expression is often performed by western blotting, a
commonly used method to measure the protein expression in neuroscience research by …

Methotrexate-loaded solid lipid nanoparticles: Protein functionalization to improve brain biodistribution

E Muntoni, K Martina, E Marini, M Giorgis, L Lazzarato… - Pharmaceutics, 2019 - mdpi.com
Glioblastoma is the most common and invasive primary tumor of the central nervous system
and normally has a negative prognosis. Biodistribution in healthy animal models is an …

Revert total protein normalization method offers a reliable loading control for mitochondrial samples following TBI

S Musyaju, HR Modi, WJ Flerlage, AH Scultetus… - Analytical …, 2023 - Elsevier
Owing to evidence that mitochondrial dysfunction plays a dominant role in the traumatic
brain injury (TBI) pathophysiology, the Western blot (WB) based immunoblotting method is …

[HTML][HTML] Common housekeeping proteins are upregulated in colorectal adenocarcinoma and hepatocellular carcinoma, making the total protein a better" housekeeper …

X Hu, S Du, J Yu, X Yang, C Yang, D Zhou, Q Wang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Housekeeping proteins are essential endogenous controls for normalization as they are
expected to be stably expressed. However, the stability of the expression level of …

Polyclonal antibodies for specific detection of tobacco host cell proteins can be efficiently generated following RuBisCO depletion and the removal of endotoxins

ZA Arfi, S Hellwig, J Drossard, R Fischer… - Biotechnology …, 2016 - Wiley Online Library
The production of biopharmaceutical proteins in plants requires efficient downstream
processing steps that remove impurities such as host cell proteins (HCPs) and adventitious …

The Inflammatory Profile in Chronic Peripheral Neuropathic Pain: Explorative studies investigating Potential Biomarker Candidates

M Jönsson - 2024 - diva-portal.org
Neuropathic pain (NeuP), a complex and debilitating pain condition caused by a lesion or
disease affecting the somatosensory system, is associated with symptoms of pathologically …

HT29 ve K562 kanser hücrelerinde protein ve metabolitlerin analizi için çeşitli analitik yöntemlerin geliştirilmesi

M Çelebier - 2013 - acikbilim.yok.gov.tr
Günümüzde tedavisi zor ve ölümcül hastalıklardan biri olan kanser, sosyal veekonomik
anlamda insanlığı tehdit etmektedir. Kanserin önlenmesi ve tedavisi ileilgili çözüm arayışları …

Untersuchung neuer Regulatoren der Glukose-stimulierten Genexpression

M Knauer - 2017 - refubium.fu-berlin.de
Das Protein Carbohydrate response element-binding protein (ChREBP) ist ein
Glukosestimulierter Transkriptionsfaktor und ein wichtiger Regulator des Glukose-und …

[图书][B] The Development of Bicyclic Peptide Library Scaffolds and the Discovery of Biostable Ligands using mRNA Display

DE Hacker - 2016 - search.proquest.com
Peptides are a promising class of therapeutic candidates due to their high specificity and
affinity for cellular protein targets. However, peptides are susceptible to protease …