Environmental risk assessment of anti-cancer drugs and their transformation products: a focus on their genotoxicity characterization-state of knowledge and short …

AP Toolaram, K Kümmerer, M Schneider - Mutation Research/Reviews in …, 2014 - Elsevier
Anti-cancer drugs are chemotherapeutic agents that are designed to kill or reduce
proliferating cells. Often times, they interfere directly or indirectly with the cell's …

Emerging pollutants

KY Bell, MJM Wells, KA Traexler… - Water Environment …, 2011 - Wiley Online Library
Water and wastewater quality research and management pertaining to emerging pollutants,
chemical or biological, for which discussion of occurrence surveys, fate and transport …

[图书][B] Chemistry of ozone in water and wastewater treatment

C Von Sonntag, U Von Gunten - 2012 - library.oapen.org
Even though ozone has been applied for a long time for disinfection and oxidation in water
treatment, there is lack of critical information related to transformation of organic compounds …

Photodegradation of the antineoplastic cyclophosphamide: a comparative study of the efficiencies of UV/H2O2, UV/Fe2+/H2O2 and UV/TiO2 processes

CA Lutterbeck, ÊL Machado, K Kümmerer - Chemosphere, 2015 - Elsevier
Anticancer drugs are harmful substances that can have carcinogenic, mutagenic,
teratogenic, genotoxic, and cytotoxic effects even at low concentrations. More than 50 years …

Occurrence of cyclophosphamide and ifosfamide in aqueous environment and their removal by biological and abiotic wastewater treatment processes

M Česen, T Kosjek, M Laimou-Geraniou… - Science of the Total …, 2015 - Elsevier
Cytostatic drug residues in the aqueous environment are of concern due to their possible
adverse effects on non-target organisms. Here we report the occurrence and removal …

Ozonation of hospital raw wastewaters for cytostatic compounds removal. Kinetic modelling and economic assessment of the process

J Ferre-Aracil, Y Valcárcel, N Negreira… - Science of The Total …, 2016 - Elsevier
The kinetics of the ozone consumption for the pretreatment of hospital wastewater has been
analysed in order to determine the reaction rate coefficients between the ozone and the …

Transformation products of antibiotic and cytostatic drugs in the aquatic cycle that result from effluent treatment and abiotic/biotic reactions in the environment: An …

T Haddad, E Baginska, K Kümmerer - Water research, 2015 - Elsevier
Pharmaceuticals may undergo transformation into new products during almost all possible
processes along their life-cycle. This could either take place in the natural water …

Ecotoxicity and genotoxicity of cyclophosphamide, ifosfamide, their metabolites/transformation products and their mixtures

M Česen, T Eleršek, M Novak, B Žegura, T Kosjek… - Environmental …, 2016 - Elsevier
Cyclophosphamide (CP) and ifosfamide (IF) are commonly used cytostatic drugs that
repress cell division by interaction with DNA. The present study investigates the ecotoxicity …

Oxidation processes for cytostatic drugs elimination in aqueous phase: A critical review

AL Garcia-Costa, A Alves, LM Madeira… - Journal of Environmental …, 2021 - Elsevier
Cancer is one of the deadliest diseases nowadays. With a continuous growth in cancer-
affected patients, the consumption of cytostatic drugs in chemotherapy is also increasing. As …

Removal of cytostatic drugs by AOPs: A review of applied processes in the context of green technology

A Pieczyńska, A Fiszka Borzyszkowska… - Critical Reviews in …, 2017 - Taylor & Francis
For decades, cytostatic drugs have been widely used in chemotherapy. However, many of
these chemicals are classified as carcinogenic, mutagenic and teratogenic compounds …