Abstract Melatonin (N‐acetyl‐5‐methoxytryptamine), an indoleamine produced in many
organs including the pineal gland, was initially characterized as a hormone primarily …

In aerobes, oxygen is essential for maintenance of life. However, incomplete reduction of
oxygen leads to generation of reactive oxygen species. These oxidants oxidise biological …

Neurodegenerative processes encompass a large variety of diseases with different
pathological patterns and clinical presentation such as Amyotrophic Lateral Sclerosis (ALS) …

Melatonin is an uncommonly widely distributed molecule. It is found throughout the plant
and animal kingdoms, ie, perhaps in every living organism. Within vertebrate organisms …

Melatonin, through its different receptors, has pleiotropic functions in mammalian brain.
Melatonin is secreted mainly by the pineal gland and exerts its effects via receptor-mediated …

The functional versatility and diversity of melatonin has exceeded everyone's expectations.
The evidence is substantial that melatonin has multiple receptor-mediated and receptor …

Metal exposure is associated with several toxic effects; herein, we review the toxicity
mechanisms of cadmium, mercury, arsenic, lead, aluminum, chromium, iron, copper, nickel …

Toxins that pass through the blood-brain barrier put neurons and glia in peril. The damage
inflicted is usually a consequence of the ability of these toxic agents to induce free radical …

In recent decades, the occurrence of chronic obstructive pulmonary disease (COPD) has
been increased remarkably in the population. Cigarette smoke (Cs) plays one of the key …

Abstract Background Higher aluminum (Al) content in infant formula and its effects on
neonatal brain development are a cause for concern. This study aimed to evaluate the …