Periodontal inflammation and systemic diseases: an overview

M Martínez-García, E Hernández-Lemus - Frontiers in physiology, 2021 - frontiersin.org
Periodontitis is a common inflammatory disease of infectious origins that often evolves into a
chronic condition. Aside from its importance as a stomatologic ailment, chronic periodontitis …

Current understanding of periodontal disease pathogenesis and targets for host‐modulation therapy

G Hajishengallis, T Chavakis… - Periodontology 2000, 2020 - Wiley Online Library
Recent advances indicate that periodontitis is driven by reciprocally reinforced interactions
between a dysbiotic microbiome and dysregulated inflammation. Inflammation is not only a …

Polymicrobial communities in periodontal disease: Their quasi‐organismal nature and dialogue with the host

G Hajishengallis, RJ Lamont - Periodontology 2000, 2021 - Wiley Online Library
In health, indigenous polymicrobial communities at mucosal surfaces maintain an ecological
balance via both inter‐microbial and host‐microbial interactions that promote their own and …

The role of inflammation and genetics in periodontal disease

BG Loos, TE Van Dyke - Periodontology 2000, 2020 - Wiley Online Library
Periodontitis is a complex disease:(a) various causative factors play a role simultaneously
and interact with each other; and (b) the disease is episodic in nature, and bursts of disease …

Periodontitis: from microbial immune subversion to systemic inflammation

G Hajishengallis - Nature reviews immunology, 2015 - nature.com
Periodontitis is a dysbiotic inflammatory disease with an adverse impact on systemic health.
Recent studies have provided insights into the emergence and persistence of dysbiotic oral …

Mental health and periodontal and peri‐implant diseases

J Ball, I Darby - Periodontology 2000, 2022 - Wiley Online Library
Mental health disorders, particularly depression and anxiety, affect a significant number of
the global population. Several pathophysiological pathways for these disorders have been …

[HTML][HTML] Herbs as an antioxidant arsenal for periodontal diseases

A Ramesh, SS Varghese, JN Doraiswamy… - Journal of …, 2016 - ncbi.nlm.nih.gov
Herbal medicines have long been used as a traditional mode of therapy for various ailments
in India. They are being used increasingly as dietary supplements to ward off common …

Immunomicrobial pathogenesis of periodontitis: keystones, pathobionts, and host response

G Hajishengallis - Trends in immunology, 2014 - cell.com
Recent studies have uncovered novel mechanisms underlying the breakdown of periodontal
host–microbe homeostasis, which can precipitate dysbiosis and periodontitis in susceptible …

Interaction of lifestyle, behaviour or systemic diseases with dental caries and periodontal diseases: consensus report of group 2 of the joint EFP/ORCA workshop on …

ILC Chapple, P Bouchard, MG Cagetti… - Journal of clinical …, 2017 - Wiley Online Library
Periodontal diseases and dental caries are the most common diseases of humans and the
main cause of tooth loss. Both diseases can lead to nutritional compromise and negative …

The inflammophilic character of the periodontitis‐associated microbiota

G Hajishengallis - Molecular oral microbiology, 2014 - Wiley Online Library
In periodontitis, dysbiotic microbial communities exhibit synergistic interactions for enhanced
protection from host defenses, nutrient acquisition, and persistence in an inflammatory …